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    Klrc3 killer cell lectin-like receptor subfamily C, member 3 [ Mus musculus (house mouse) ]

    Gene ID: 58179, updated on 25-Nov-2021

    Summary

    Official Symbol
    Klrc3provided by MGI
    Official Full Name
    killer cell lectin-like receptor subfamily C, member 3provided by MGI
    Primary source
    MGI:MGI:1929720
    See related
    Ensembl:ENSMUSG00000033027
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Klrc2; Nkg2e
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See Klrc3 in Genome Data Viewer
    Location:
    6; 6 F3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (129613226..129620474, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (129636263..129643511, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (129589103..129593306, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene killer cell lectin-like receptor, subfamily D, member 1 Neighboring gene killer cell lectin-like receptor subfamily K, member 1 Neighboring gene killer cell lectin-like receptor subfamily C, member 2 Neighboring gene killer cell lectin-like receptor subfamily C, member 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1)  1 citation
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables HLA-E specific inhibitory MHC class Ib receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables MHC class I protein complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables activating MHC class Ib receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein antigen binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transmembrane signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in external side of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of receptor complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    killer cell lectin-like receptor subfamily C, member 3
    Names
    killer cell lectin-like receptor subfamily C, member 2
    natural killer cell group 2E cell receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021378.1NP_067353.1  killer cell lectin-like receptor subfamily C, member 3

      See identical proteins and their annotated locations for NP_067353.1

      Status: PROVISIONAL

      Source sequence(s)
      AF195779
      Consensus CDS
      CCDS20591.1
      UniProtKB/TrEMBL
      Q9QXN7
      Related
      ENSMUSP00000071147.6, ENSMUST00000071149.7
      Conserved Domains (2) summary
      cd03593
      Location:105217
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
      PHA03097
      Location:65220
      PHA03097; C-type lectin-like protein; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      129613226..129620474 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006506430.2XP_006506493.1  killer cell lectin-like receptor subfamily C, member 3 isoform X1

      Conserved Domains (1) summary
      cd03593
      Location:130242
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
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