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    cpe carboxypeptidase E [ Danio rerio (zebrafish) ]

    Gene ID: 407979, updated on 6-May-2021

    Summary

    Official Symbol
    cpeprovided by ZNC
    Official Full Name
    carboxypeptidase Eprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090313-68
    See related
    Ensembl:ENSDARG00000055874
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:85981; si:ch211-198g9.2
    Orthologs
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    Genomic context

    See cpe in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (20866858..20911278, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (20173921..20218393, complement)
    103 previous assembly Zv9 (GCF_000002035.4) 1 NC_007112.5 (19648162..19692640, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 Neighboring gene tolloid-like 1 Neighboring gene si:dkeyp-72g6.2 Neighboring gene methylsterol monooxygenase 1 Neighboring gene kelch-like family member 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metallocarboxypeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables metallocarboxypeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in peptide metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    carboxypeptidase E
    NP_999975.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214810.2NP_999975.1  carboxypeptidase E precursor

      See identical proteins and their annotated locations for NP_999975.1

      Status: VALIDATED

      Source sequence(s)
      BX119983, CT583646
      UniProtKB/TrEMBL
      Q6NSM5
      Related
      ENSDARP00000072733.5, ENSDART00000078271.6
      Conserved Domains (2) summary
      cd03865
      Location:27349
      M14_CPE; Peptidase M14 carboxypeptidase subfamily N/E-like; Carboxypeptidase E subgroup
      cd11308
      Location:353425
      Peptidase_M14NE-CP-C_like; Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      20866858..20911278 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394476.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      123070..167593 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395211.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      4610..4999 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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