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    Spib Spi-B transcription factor (Spi-1/PU.1 related) [ Mus musculus (house mouse) ]

    Gene ID: 272382, updated on 16-Oct-2021

    Summary

    Official Symbol
    Spibprovided by MGI
    Official Full Name
    Spi-B transcription factor (Spi-1/PU.1 related)provided by MGI
    Primary source
    MGI:MGI:892986
    See related
    Ensembl:ENSMUSG00000008193
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Spi-B
    Expression
    Biased expression in spleen adult (RPKM 101.9), mammary gland adult (RPKM 21.1) and 2 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Spib in Genome Data Viewer
    Location:
    7 B3; 7 28.83 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (44175419..44181511, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (44525995..44532087, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (51781365..51787441, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene ER membrane protein complex subunit 10 Neighboring gene family with sequence similarity 71, member E1 Neighboring gene myosin binding protein C, fast-type Neighboring gene polymerase (DNA directed), delta 1, catalytic subunit Neighboring gene microRNA 7053 Neighboring gene nuclear receptor subfamily 1, group H, member 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of transcription regulator complex IC
    Inferred by Curator
    more info
    PubMed 

    General protein information

    Preferred Names
    transcription factor Spi-B
    Names
    Ets transcription factor Spi-B
    Spi-1/PU.1 related

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019866.1NP_063919.1  transcription factor Spi-B

      See identical proteins and their annotated locations for NP_063919.1

      Status: VALIDATED

      Source sequence(s)
      CAAA01070168
      Consensus CDS
      CCDS21209.1
      UniProtKB/Swiss-Prot
      O35906
      Related
      ENSMUSP00000035539.5, ENSMUST00000035323.6
      Conserved Domains (1) summary
      smart00413
      Location:173261
      ETS; erythroblast transformation specific domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      44175419..44181511 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030242628.1XP_030098488.1  transcription factor Spi-B isoform X7

      Conserved Domains (1) summary
      smart00413
      Location:155243
      ETS; erythroblast transformation specific domain
    2. XM_006540939.3XP_006541002.1  transcription factor Spi-B isoform X9

    3. XM_006540933.3XP_006540996.1  transcription factor Spi-B isoform X2

      UniProtKB/Swiss-Prot
      O35906
      Related
      ENSMUSP00000096084.4, ENSMUST00000098483.9
      Conserved Domains (1) summary
      smart00413
      Location:191279
      ETS; erythroblast transformation specific domain
    4. XM_006540938.4XP_006541001.1  transcription factor Spi-B isoform X8

    5. XM_006540934.4XP_006540997.1  transcription factor Spi-B isoform X4

      Conserved Domains (1) summary
      smart00413
      Location:174262
      ETS; erythroblast transformation specific domain
    6. XM_006540932.5XP_006540995.1  transcription factor Spi-B isoform X1

      Conserved Domains (1) summary
      smart00413
      Location:192280
      ETS; erythroblast transformation specific domain
    7. XM_030242627.2XP_030098487.1  transcription factor Spi-B isoform X6

      Conserved Domains (1) summary
      smart00413
      Location:156244
      ETS; erythroblast transformation specific domain
    8. XM_006540935.5XP_006540998.1  transcription factor Spi-B isoform X3

      UniProtKB/Swiss-Prot
      O35906
      Related
      ENSMUSP00000145968.2, ENSMUST00000205506.2
      Conserved Domains (1) summary
      smart00413
      Location:174262
      ETS; erythroblast transformation specific domain
    9. XM_006540936.4XP_006540999.1  transcription factor Spi-B isoform X5

      Conserved Domains (1) summary
      smart00413
      Location:164252
      ETS; erythroblast transformation specific domain
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