Format

Send to:

Choose Destination
    • Showing Current items.

    Npy5r neuropeptide Y receptor Y5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25340, updated on 30-Sep-2021

    Summary

    Official Symbol
    Npy5rprovided by RGD
    Official Full Name
    neuropeptide Y receptor Y5provided by RGD
    Primary source
    RGD:3199
    See related
    EnsemblRapid:ENSRNOG00000014172
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    NPYR5
    Summary
    receptor for neuropeptide Y and neuropeptide Y Y1; may be involved in regulation of energy homeostasis [RGD, Feb 2006]
    Expression
    Restricted expression toward (RPKM 14.9) See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Npy5r in Genome Data Viewer
    Location:
    16p14
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    108 current mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (23055427..23063384)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (24796685..24805730)

    Chromosome 16 - NC_051351.1Genomic Context describing neighboring genes Neighboring gene nuclear assembly factor 1 ribonucleoprotein Neighboring gene neuropeptide Y receptor Y1 Neighboring gene U7 small nuclear RNA Neighboring gene transketolase-like 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables neuropeptide Y receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables neuropeptide Y receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables pancreatic polypeptide receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables pancreatic polypeptide receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables pancreatic polypeptide receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables peptide YY receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables peptide YY receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables peptide YY receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in aging IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in cardiac left ventricle morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in chemical synaptic transmission IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within chemical synaptic transmission ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in eating behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in generation of ovulation cycle rhythm IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of acute inflammatory response to antigenic stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of glutamate secretion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of synaptic transmission, GABAergic IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in outflow tract morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of ERK1 and ERK2 cascade IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of acute inflammatory response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of cell population proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of smooth muscle cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in neuron projection ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    neuropeptide Y receptor type 5
    Names
    NPY-Y5 receptor
    NPY5-R
    NPYY5-R
    Neuropeptide Y5 receptor
    Y5 receptor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012869.2NP_037001.1  neuropeptide Y receptor type 5

      See identical proteins and their annotated locations for NP_037001.1

      Status: PROVISIONAL

      Source sequence(s)
      JACYVU010000279
      UniProtKB/Swiss-Prot
      Q63634
      Related
      ENSRNOP00000018976.2, ENSRNOT00000018976.4
      Conserved Domains (2) summary
      pfam00001
      Location:58424
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:52170
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mRatBN7.2 Primary Assembly

    Genomic

    1. NC_051351.1 Reference mRatBN7.2 Primary Assembly

      Range
      23055427..23063384
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006253014.4XP_006253076.1  neuropeptide Y receptor type 5 isoform X1

      See identical proteins and their annotated locations for XP_006253076.1

      UniProtKB/Swiss-Prot
      Q63634
      Related
      ENSRNOP00000086593.1, ENSRNOT00000109751.1
      Conserved Domains (2) summary
      pfam00001
      Location:58424
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:52170
      7tm_4; Olfactory receptor
    Support Center