Format

Send to:

Choose Destination
    • Showing Current items.

    Defb15 defensin beta 15 [ Mus musculus (house mouse) ]

    Gene ID: 246082, updated on 23-Jun-2021

    Summary

    Official Symbol
    Defb15provided by MGI
    Official Full Name
    defensin beta 15provided by MGI
    Primary source
    MGI:MGI:2179202
    See related
    Ensembl:ENSMUSG00000048500
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BD-15
    Expression
    Restricted expression toward genital fat pad adult (RPKM 61.7) See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Defb15 in Genome Data Viewer
    Location:
    8; 8 A2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (22419829..22422726, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (21929813..21932710, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (23040285..23043182, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene defensin beta 9 Neighboring gene defensin beta 11 Neighboring gene defensin beta 35 Neighboring gene predicted gene, 29821 Neighboring gene defensin beta 13

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables CCR2 chemokine receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables heparin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables lipopolysaccharide binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in antifungal innate immune response ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within defense response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in defense response to Gram-negative bacterium ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in defense response to Gram-positive bacterium ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within defense response to bacterium IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in innate immune response ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extrinsic component of membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in microvesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_139222.3NP_631968.1  beta-defensin 15 precursor

      See identical proteins and their annotated locations for NP_631968.1

      Status: VALIDATED

      Source sequence(s)
      AJ437648
      Consensus CDS
      CCDS40288.1
      UniProtKB/Swiss-Prot
      Q8R2I5
      Related
      ENSMUSP00000059763.3, ENSMUST00000062586.3
      Conserved Domains (1) summary
      pfam13841
      Location:2554
      Defensin_beta_2; Beta defensin

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      22419829..22422726 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center