Format

Send to:

Choose Destination
    • Showing Current items.

    Plekhg6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 [ Mus musculus (house mouse) ]

    Gene ID: 213522, updated on 23-Jun-2021

    Summary

    Official Symbol
    Plekhg6provided by MGI
    Official Full Name
    pleckstrin homology domain containing, family G (with RhoGef domain) member 6provided by MGI
    Primary source
    MGI:MGI:2682298
    See related
    Ensembl:ENSMUSG00000038167
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm155; BC026778
    Expression
    Biased expression in duodenum adult (RPKM 20.7), small intestine adult (RPKM 19.3) and 10 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Plekhg6 in Genome Data Viewer
    Location:
    6; 6 F3
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (125339614..125358578, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (125362651..125381615, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (125312669..125330522, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene lymphotoxin B receptor Neighboring gene sodium channel, nonvoltage-gated 1 alpha Neighboring gene tumor necrosis factor receptor superfamily, member 1a Neighboring gene predicted gene, 52918 Neighboring gene predicted gene, 32673 Neighboring gene CD9 antigen Neighboring gene predicted gene 28809

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Clone Names

    • MGC30363

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    pleckstrin homology domain-containing family G member 6
    Names
    PH domain-containing family G member 6

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198604.2NP_941006.2  pleckstrin homology domain-containing family G member 6

      See identical proteins and their annotated locations for NP_941006.2

      Status: VALIDATED

      Source sequence(s)
      AC140324, AK153619
      Consensus CDS
      CCDS39642.1
      UniProtKB/Swiss-Prot
      Q8R0J1
      Related
      ENSMUSP00000037004.7, ENSMUST00000042647.7
      Conserved Domains (2) summary
      cd13244
      Location:408505
      PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
      pfam00621
      Location:165351
      RhoGEF; RhoGEF domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      125339614..125358578 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006505867.3XP_006505930.1  pleckstrin homology domain-containing family G member 6 isoform X1

      See identical proteins and their annotated locations for XP_006505930.1

      UniProtKB/Swiss-Prot
      Q8R0J1
      Conserved Domains (2) summary
      cd13244
      Location:408505
      PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
      pfam00621
      Location:165351
      RhoGEF; RhoGEF domain
    2. XM_017321495.2XP_017176984.1  pleckstrin homology domain-containing family G member 6 isoform X2

      Conserved Domains (2) summary
      smart00325
      Location:165319
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd13244
      Location:376473
      PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    Support Center