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    Tspoap1 TSPO associated protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 207777, updated on 25-Nov-2021

    Summary

    Official Symbol
    Tspoap1provided by MGI
    Official Full Name
    TSPO associated protein 1provided by MGI
    Primary source
    MGI:MGI:2450877
    See related
    Ensembl:ENSMUSG00000034156
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bzrap1; PRAX-1; mKIAA0612; D230016K05
    Expression
    Biased expression in frontal lobe adult (RPKM 29.5), cortex adult (RPKM 26.7) and 7 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Tspoap1 in Genome Data Viewer
    Location:
    11; 11 C
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (87649022..87676754)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (87758194..87785928)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (87574043..87599430)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene SPT4A, DSIF elongation factor subunit Neighboring gene microRNA 142b Neighboring gene microRNA 142 Neighboring gene Mpo distal enhancer region Neighboring gene Mpo proximal enhancer and promoter region Neighboring gene myeloperoxidase

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2)  1 citation
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    NOT involved_in neuromuscular synaptic transmission IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in calyx of Held IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in calyx of Held IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    peripheral-type benzodiazepine receptor-associated protein 1
    Names
    PBR-IP
    RIM-BP1
    RIMS-binding protein 1
    benzodiazapine receptor associated protein 1
    benzodiazepine receptor associated protein 1
    peripheral benzodiazepine receptor-associated protein 1
    peripheral benzodiazepine receptor-interacting protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172449.2NP_766037.2  peripheral-type benzodiazepine receptor-associated protein 1

      See identical proteins and their annotated locations for NP_766037.2

      Status: VALIDATED

      Source sequence(s)
      AK043747, BC055691, BQ769688, BY233070, CA317177, CB249809, CD348883, CN460580, CN525117, CO429655, EL605892
      Consensus CDS
      CCDS48879.1
      UniProtKB/Swiss-Prot
      Q7TNF8
      Related
      ENSMUSP00000048063.6, ENSMUST00000039627.12
      Conserved Domains (9) summary
      cd12012
      Location:16201681
      SH3_RIM-BP_2; Second Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12013
      Location:17601819
      SH3_RIM-BP_3; Third Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12014
      Location:653713
      SH3_RIM-BP_1; First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd00063
      Location:881943
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam05837
      Location:127232
      CENP-H; Centromere protein H (CENP-H)
      pfam08614
      Location:58183
      ATG16; Autophagy protein 16 (ATG16)
      pfam09728
      Location:147510
      Taxilin; Myosin-like coiled-coil protein
      cl02488
      Location:330518
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl23720
      Location:427519
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      87649022..87676754
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532703.5XP_006532766.1  peripheral-type benzodiazepine receptor-associated protein 1 isoform X2

      Conserved Domains (7) summary
      cd12012
      Location:16131674
      SH3_RIM-BP_2; Second Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12013
      Location:17651824
      SH3_RIM-BP_3; Third Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12014
      Location:646706
      SH3_RIM-BP_1; First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      PHA03247
      Location:13321723
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:158496
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00063
      Location:874936
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam08614
      Location:123183
      ATG16; Autophagy protein 16 (ATG16)
    2. XM_006532702.5XP_006532765.1  peripheral-type benzodiazepine receptor-associated protein 1 isoform X1

      Conserved Domains (7) summary
      cd12012
      Location:16201681
      SH3_RIM-BP_2; Second Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12013
      Location:17721831
      SH3_RIM-BP_3; Third Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12014
      Location:653713
      SH3_RIM-BP_1; First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      PHA03247
      Location:13391730
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:158501
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00063
      Location:881943
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam08614
      Location:123183
      ATG16; Autophagy protein 16 (ATG16)
    3. XM_030245745.2XP_030101605.1  peripheral-type benzodiazepine receptor-associated protein 1 isoform X8

      Conserved Domains (6) summary
      cd12012
      Location:13401401
      SH3_RIM-BP_2; Second Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12013
      Location:14921551
      SH3_RIM-BP_3; Third Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12014
      Location:653713
      SH3_RIM-BP_1; First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      COG1196
      Location:158501
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00063
      Location:881943
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam08614
      Location:123183
      ATG16; Autophagy protein 16 (ATG16)
    4. XM_006532709.5XP_006532772.1  peripheral-type benzodiazepine receptor-associated protein 1 isoform X6

      Conserved Domains (6) summary
      cd12012
      Location:13401401
      SH3_RIM-BP_2; Second Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12013
      Location:14921551
      SH3_RIM-BP_3; Third Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12014
      Location:653713
      SH3_RIM-BP_1; First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      COG1196
      Location:158501
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00063
      Location:881943
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam08614
      Location:123183
      ATG16; Autophagy protein 16 (ATG16)
    5. XM_006532710.5XP_006532773.1  peripheral-type benzodiazepine receptor-associated protein 1 isoform X9

      UniProtKB/Swiss-Prot
      Q7TNF8
      Conserved Domains (6) summary
      cd12012
      Location:13401401
      SH3_RIM-BP_2; Second Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12013
      Location:14801539
      SH3_RIM-BP_3; Third Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12014
      Location:653713
      SH3_RIM-BP_1; First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      COG1196
      Location:158501
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00063
      Location:881943
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam08614
      Location:123183
      ATG16; Autophagy protein 16 (ATG16)
    6. XM_036156489.1XP_036012382.1  peripheral-type benzodiazepine receptor-associated protein 1 isoform X7

      Conserved Domains (6) summary
      cd12012
      Location:13401401
      SH3_RIM-BP_2; Second Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12013
      Location:14801539
      SH3_RIM-BP_3; Third Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12014
      Location:653713
      SH3_RIM-BP_1; First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      COG1196
      Location:158501
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00063
      Location:881943
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam08614
      Location:123183
      ATG16; Autophagy protein 16 (ATG16)
    7. XM_006532706.3XP_006532769.1  peripheral-type benzodiazepine receptor-associated protein 1 isoform X4

      Conserved Domains (7) summary
      cd12012
      Location:16201681
      SH3_RIM-BP_2; Second Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12013
      Location:17721831
      SH3_RIM-BP_3; Third Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12014
      Location:653713
      SH3_RIM-BP_1; First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      PHA03247
      Location:13391730
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:158501
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00063
      Location:881943
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam08614
      Location:123183
      ATG16; Autophagy protein 16 (ATG16)
    8. XM_006532704.3XP_006532767.1  peripheral-type benzodiazepine receptor-associated protein 1 isoform X3

      Conserved Domains (7) summary
      cd12012
      Location:16201681
      SH3_RIM-BP_2; Second Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12013
      Location:17601819
      SH3_RIM-BP_3; Third Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12014
      Location:653713
      SH3_RIM-BP_1; First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      PHA03247
      Location:13391730
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:158501
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00063
      Location:881943
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam08614
      Location:123183
      ATG16; Autophagy protein 16 (ATG16)
    9. XM_006532708.4XP_006532771.1  peripheral-type benzodiazepine receptor-associated protein 1 isoform X5

      Conserved Domains (6) summary
      cd12012
      Location:13651426
      SH3_RIM-BP_2; Second Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12013
      Location:15171576
      SH3_RIM-BP_3; Third Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12014
      Location:398458
      SH3_RIM-BP_1; First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      PHA03247
      Location:10841475
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:626688
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      TIGR02168
      Location:58269
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    10. XM_006532712.2XP_006532775.1  peripheral-type benzodiazepine receptor-associated protein 1 isoform X10

      See identical proteins and their annotated locations for XP_006532775.1

      Conserved Domains (6) summary
      cd12012
      Location:11841245
      SH3_RIM-BP_2; Second Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12013
      Location:13361395
      SH3_RIM-BP_3; Third Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12014
      Location:217277
      SH3_RIM-BP_1; First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      PHA03247
      Location:9001294
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:445507
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00769
      Location:184
      ERM; Ezrin/radixin/moesin family
    11. XM_030245746.2XP_030101606.1  peripheral-type benzodiazepine receptor-associated protein 1 isoform X11

      Conserved Domains (6) summary
      cd12012
      Location:11771238
      SH3_RIM-BP_2; Second Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12013
      Location:13291388
      SH3_RIM-BP_3; Third Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12014
      Location:210270
      SH3_RIM-BP_1; First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      PHA03247
      Location:8961287
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:377
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00063
      Location:438500
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    12. XM_006532711.1XP_006532774.1  peripheral-type benzodiazepine receptor-associated protein 1 isoform X10

      See identical proteins and their annotated locations for XP_006532774.1

      Conserved Domains (6) summary
      cd12012
      Location:11841245
      SH3_RIM-BP_2; Second Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12013
      Location:13361395
      SH3_RIM-BP_3; Third Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      cd12014
      Location:217277
      SH3_RIM-BP_1; First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins
      PHA03247
      Location:9001294
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:445507
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00769
      Location:184
      ERM; Ezrin/radixin/moesin family
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