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    Ms4a1 membrane-spanning 4-domains, subfamily A, member 1 [ Mus musculus (house mouse) ]

    Gene ID: 12482, updated on 16-Oct-2021

    Summary

    Official Symbol
    Ms4a1provided by MGI
    Official Full Name
    membrane-spanning 4-domains, subfamily A, member 1provided by MGI
    Primary source
    MGI:MGI:88321
    See related
    Ensembl:ENSMUSG00000024673
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cd20; Ly-44; Ms4a2; AA960661
    Expression
    Biased expression in spleen adult (RPKM 13.9), mammary gland adult (RPKM 3.4) and 2 other tissues See more
    Orthologs
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    Genomic context

    See Ms4a1 in Genome Data Viewer
    Location:
    19 A; 19 8.19 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (11227043..11243513, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (11249679..11266149, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (11325093..11340641, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene membrane-spanning 4-domains, subfamily A, member 13 Neighboring gene RIKEN cDNA 4930526L06 gene Neighboring gene membrane-spanning 4-domains, subfamily A, member 12 Neighboring gene membrane-spanning 4-domains, subfamily A, member 5 Neighboring gene membrane-spanning 4-domains, subfamily A, member 14

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables epidermal growth factor receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables immunoglobulin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in B cell activation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in B cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in B cell receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in calcium ion import into cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in calcium ion import into cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein tetramerization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within response to bacterium IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in store-operated calcium entry ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    located_in external side of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in integral component of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane raft ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    B-lymphocyte antigen CD20
    Names
    B-cell differentiation antigen Ly-44
    CD20 antigen
    lymphocyte antigen 44
    membrane-spanning 4-domains, subfamily A, member 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007641.6NP_031667.1  B-lymphocyte antigen CD20

      See identical proteins and their annotated locations for NP_031667.1

      Status: VALIDATED

      Source sequence(s)
      AK017903, AK080148, BE687007
      Consensus CDS
      CCDS37923.1
      UniProtKB/Swiss-Prot
      P19437
      UniProtKB/TrEMBL
      Q542S5
      Related
      ENSMUSP00000126422.2, ENSMUST00000169159.3
      Conserved Domains (1) summary
      pfam04103
      Location:44210
      CD20; CD20-like family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      11227043..11243513 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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