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    Pwp2 PWP2 periodic tryptophan protein homolog (yeast) [ Mus musculus (house mouse) ]

    Gene ID: 110816, updated on 16-Oct-2021

    Summary

    Official Symbol
    Pwp2provided by MGI
    Official Full Name
    PWP2 periodic tryptophan protein homolog (yeast)provided by MGI
    Primary source
    MGI:MGI:1341200
    See related
    Ensembl:ENSMUSG00000032834
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pwp2h; wdp103; 6530411D08Rik
    Expression
    Ubiquitous expression in ovary adult (RPKM 6.6), CNS E18 (RPKM 6.0) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Pwp2 in Genome Data Viewer
    Location:
    10 C1; 10 39.72 cM
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (78006743..78021005, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (78170909..78185171, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (77633655..77647894, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 47922 Neighboring gene glutamine amidotransferase like class 1 domain containing 3A Neighboring gene trafficking protein particle complex 10 Neighboring gene predicted gene, 30122

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC117973

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in ribosomal small subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of Pwp2p-containing subcomplex of 90S preribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    periodic tryptophan protein 2 homolog
    Names
    WD-repeat protein p103

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029546.2NP_083822.1  periodic tryptophan protein 2 homolog

      See identical proteins and their annotated locations for NP_083822.1

      Status: PROVISIONAL

      Source sequence(s)
      AK088254
      Consensus CDS
      CCDS35958.1
      UniProtKB/Swiss-Prot
      Q8BU03
      UniProtKB/TrEMBL
      Q2M1K2
      Related
      ENSMUSP00000045812.10, ENSMUST00000042556.11
      Conserved Domains (5) summary
      COG2319
      Location:277643
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:322629
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam04003
      Location:771873
      Utp12; Dip2/Utp12 Family
      sd00039
      Location:333371
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:20401
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      78006743..78021005 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_001779417.1 RNA Sequence

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