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    Mien1 migration and invasion enhancer 1 [ Mus musculus (house mouse) ]

    Gene ID: 103742, updated on 23-Jun-2021

    Summary

    Official Symbol
    Mien1provided by MGI
    Official Full Name
    migration and invasion enhancer 1provided by MGI
    Primary source
    MGI:MGI:1913678
    See related
    Ensembl:ENSMUSG00000002580
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rdx12; AI463380; 1810046J19Rik
    Expression
    Ubiquitous expression in genital fat pad adult (RPKM 66.7), duodenum adult (RPKM 55.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Mien1 in Genome Data Viewer
    Location:
    11; 11 D
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (98328534..98349056, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (98437708..98458230, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (98299022..98300302, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene phenylethanolamine-N-methyltransferase Neighboring gene post-GPI attachment to proteins 3 Neighboring gene erb-b2 receptor tyrosine kinase 2 Neighboring gene growth factor receptor bound protein 7 Neighboring gene IKAROS family zinc finger 3 Neighboring gene predicted gene, 25106 Neighboring gene VISTA enhancer mm503

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of filopodium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of filopodium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to selenium ion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intrinsic component of the cytoplasmic side of the plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    migration and invasion enhancer 1
    Names
    protein C17orf37 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025559.2NP_079835.1  migration and invasion enhancer 1

      See identical proteins and their annotated locations for NP_079835.1

      Status: VALIDATED

      Source sequence(s)
      AK007795, BE623929, CA530220
      Consensus CDS
      CCDS25350.1
      UniProtKB/Swiss-Prot
      Q9CQ86
      Related
      ENSMUSP00000002655.8, ENSMUST00000002655.8
      Conserved Domains (1) summary
      TIGR02174
      Location:2595
      CXXU_selWTH; selT/selW/selH selenoprotein domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      98328534..98349056 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030245455.1XP_030101315.1  migration and invasion enhancer 1 isoform X1

      Conserved Domains (1) summary
      TIGR02174
      Location:2595
      CXXU_selWTH; selT/selW/selH selenoprotein domain
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