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    elp3 elongator acetyltransferase complex subunit 3 [ Danio rerio (zebrafish) ]

    Gene ID: 541509, updated on 5-Jan-2022

    Summary

    Official Symbol
    elp3provided by ZNC
    Official Full Name
    elongator acetyltransferase complex subunit 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050327-35
    See related
    Ensembl:ENSDARG00000042005
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:113140; si:ch211-63o20.8
    Summary
    Predicted to enable phosphorylase kinase regulator activity and tRNA uridine(34) acetyltransferase activity. Acts upstream of or within axonogenesis and somite development. Predicted to be part of elongator holoenzyme complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human ELP3 (elongator acetyltransferase complex subunit 3). [provided by Alliance of Genome Resources, Nov 2021]
    Orthologs
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    Genomic context

    See elp3 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (34671396..34700654)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (34768517..34797775)
    103 previous assembly Zv9 (GCF_000002035.4) 20 NC_007131.5 (34696004..34725262)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene si:ch211-63o20.10 Neighboring gene solute carrier family 25 member 24 Neighboring gene si:ch211-63o20.7 Neighboring gene prepronociceptin b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables 2-methylhexanoyl-CoA C-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables N-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables keto acid formate lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidyl-lysine N6-palmitoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphorylase kinase regulator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables tRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables tRNA uridine(34) acetyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within nervous system development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within somite development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within tRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in tRNA wobble uridine modification ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of elongator holoenzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    elongator complex protein 3
    Names
    elongation protein 3 homolog
    tRNA uridine(34) acetyltransferase
    NP_001014344.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014322.2NP_001014344.2  elongator complex protein 3

      See identical proteins and their annotated locations for NP_001014344.2

      Status: PROVISIONAL

      Source sequence(s)
      BC096810
      UniProtKB/Swiss-Prot
      Q5RIC0
      UniProtKB/TrEMBL
      B2GS73
      Related
      ENSDARP00000113240.2, ENSDART00000138226.3
      Conserved Domains (1) summary
      TIGR01211
      Location:37547
      ELP3; radical SAM enzyme/protein acetyltransferase, ELP3 family

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      34671396..34700654
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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