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    TIM triosephosphate isomerase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816652, updated on 8-Jul-2021

    Summary

    Gene symbol
    TIM
    Gene description
    triosephosphate isomerase
    Primary source
    Araport:AT2G21170
    Locus tag
    AT2G21170
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F26H11.7; F26H11_7; PDTPI; PLASTID ISOFORM TRIOSE PHOSPHATE ISOMERASE; triosephosphate isomerase; TRIOSEPHOSPHATE ISOMERASE
    Summary
    Encodes a plastidic triose phosphate isomerase. Mutants with reduced pdTPI levels have difficulty transitioning from heterotrophic to autotrophic growth. The related phenotypes, such as chlorosis in light-grown seedlings may result from an accumulation of dihydroxyacetone phosphate (DHAP) and methylglyoxal (MG) in these mutants. Both splice variants appear to be expressed, but the At2g21170.2 variant appears to have a much narrower expression range limited to roots.
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    Genomic context

    See TIM in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    10
    Sequence:
    Chromosome: 2; NC_003071.7 (9070734..9074470, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene XAP5 family protein Neighboring gene Translocon-associated protein (TRAP), alpha subunit Neighboring gene miscRNA Neighboring gene transmembrane protein Neighboring gene ncRNA Neighboring gene transmembrane protein

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    NM_001084462.1
    NM_001335732.1
    NM_127687.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables triose-phosphate isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables triose-phosphate isomerase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables triose-phosphate isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    triosephosphate isomerase
    NP_001077931.1
    • triosephosphate isomerase (TIM); FUNCTIONS IN: triose-phosphate isomerase activity; INVOLVED IN: in 7 processes; LOCATED IN: thylakoid, mitochondrion, apoplast, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Triosephosphate isomerase, active site (InterPro:IPR020861), Aldolase-type TIM barrel (InterPro:IPR013785), Triosephosphate isomerase (InterPro:IPR000652); BEST Arabidopsis thaliana protein match is: triosephosphate isomerase (TAIR:AT3G55440.1); Has 11527 Blast hits to 11525 proteins in 3623 species: Archae - 144; Bacteria - 6185; Metazoa - 1204; Fungi - 240; Plants - 472; Viruses - 0; Other Eukaryotes - 3282 (source: NCBI BLink).
    NP_179713.1
    • triosephosphate isomerase (TIM); FUNCTIONS IN: triose-phosphate isomerase activity; INVOLVED IN: in 7 processes; LOCATED IN: in 6 components; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Triosephosphate isomerase, active site (InterPro:IPR020861), Aldolase-type TIM barrel (InterPro:IPR013785), Triosephosphate isomerase (InterPro:IPR000652); BEST Arabidopsis thaliana protein match is: triosephosphate isomerase (TAIR:AT3G55440.1); Has 11587 Blast hits to 11585 proteins in 3635 species: Archae - 138; Bacteria - 6210; Metazoa - 1207; Fungi - 243; Plants - 472; Viruses - 0; Other Eukaryotes - 3317 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      9070734..9074470 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127687.4NP_179713.1  triosephosphate isomerase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179713.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SKP6
      UniProtKB/TrEMBL
      A0A178VN28
      Conserved Domains (1) summary
      PLN02429
      Location:1315
      PLN02429; triosephosphate isomerase
    2. NM_001335732.1NP_001323967.1  triosephosphate isomerase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SKP6
      UniProtKB/TrEMBL
      A0A178VN28
      Conserved Domains (1) summary
      PLN02429
      Location:1315
      PLN02429; triosephosphate isomerase
    3. NM_001084462.1NP_001077931.1  triosephosphate isomerase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077931.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8MRE8
      Conserved Domains (1) summary
      PLN02429
      Location:1306
      PLN02429; triosephosphate isomerase
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