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    MIEN1 migration and invasion enhancer 1 [ Homo sapiens (human) ]

    Gene ID: 84299, updated on 5-Sep-2021

    Summary

    Official Symbol
    MIEN1provided by HGNC
    Official Full Name
    migration and invasion enhancer 1provided by HGNC
    Primary source
    HGNC:HGNC:28230
    See related
    Ensembl:ENSG00000141741 MIM:611802
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C35; ORB3; XTP4; RDX12; C17orf37
    Expression
    Ubiquitous expression in colon (RPKM 15.4), esophagus (RPKM 14.3) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See MIEN1 in Genome Data Viewer
    Location:
    17q12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (39728510..39730532, complement)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (37884763..37886785, complement)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene VISTA enhancer hs1769 Neighboring gene post-GPI attachment to proteins phospholipase 3 Neighboring gene erb-b2 receptor tyrosine kinase 2 Neighboring gene microRNA 4728 Neighboring gene growth factor receptor bound protein 7 Neighboring gene IKAROS family zinc finger 3 Neighboring gene keratin 8 pseudogene 34

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC14832

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in negative regulation of apoptotic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of cell migration IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of filopodium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of filopodium assembly IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in response to selenium ion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in centriolar satellite IDA
    Inferred from Direct Assay
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in intrinsic component of the cytoplasmic side of the plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
     

    General protein information

    Preferred Names
    migration and invasion enhancer 1
    Names
    HBV X-transactivated gene 4 protein
    HBV XAg-transactivated protein 4
    protein C17orf37

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001330206.2NP_001317135.1  migration and invasion enhancer 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC079199, AY508814, BC063395, CR986467
      Consensus CDS
      CCDS82115.1
      UniProtKB/Swiss-Prot
      Q9BRT3
      UniProtKB/TrEMBL
      J3KTI2
      Related
      ENSP00000462998.1, ENST00000577810.1
      Conserved Domains (1) summary
      TIGR02174
      Location:2589
      CXXU_selWTH; selT/selW/selH selenoprotein domain
    2. NM_032339.5NP_115715.3  migration and invasion enhancer 1 isoform 1

      See identical proteins and their annotated locations for NP_115715.3

      Status: VALIDATED

      Source sequence(s)
      AC079199, AY508814, BC006006, BC063395
      Consensus CDS
      CCDS11344.1
      UniProtKB/Swiss-Prot
      Q9BRT3
      Related
      ENSP00000377778.3, ENST00000394231.8
      Conserved Domains (1) summary
      TIGR02174
      Location:2595
      CXXU_selWTH; selT/selW/selH selenoprotein domain

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

      Range
      39728510..39730532 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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