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    Rab14 RAB14, member RAS oncogene family [ Mus musculus (house mouse) ]

    Gene ID: 68365, updated on 3-Oct-2021

    Summary

    Official Symbol
    Rab14provided by MGI
    Official Full Name
    RAB14, member RAS oncogene familyprovided by MGI
    Primary source
    MGI:MGI:1915615
    See related
    Ensembl:ENSMUSG00000026878
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI314285; AI649155; 0610030G24Rik; 2810475J17Rik; A830021G03Rik; D030017L14Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 151.4), stomach adult (RPKM 60.7) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rab14 in Genome Data Viewer
    Location:
    2; 2 B
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (35070217..35091132, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (35180205..35201120, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (35035725..35056640, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene expressed sequence AI182371 Neighboring gene centriolin Neighboring gene predicted gene 13605 Neighboring gene predicted gene, 52553 Neighboring gene predicted gene, 39795 Neighboring gene gelsolin

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GDP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTPase activity TAS
    Traceable Author Statement
    more info
     
    enables myosin V binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in Golgi to endosome transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in Golgi to endosome transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in apical protein localization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in body fluid secretion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in defense response to bacterium IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in endocytic recycling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in fibroblast growth factor receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in phagolysosome assembly involved in apoptotic cell clearance IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in phagosome maturation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of protein localization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi stack ISO
    Inferred from Sequence Orthology
    more info
     
    located_in alveolar lamellar body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle membrane TAS
    Traceable Author Statement
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in early endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in early endosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in late endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear outer membrane-endoplasmic reticulum membrane network ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in phagocytic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in phagocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in recycling endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in rough endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in trans-Golgi network IEA
    Inferred from Electronic Annotation
    more info
     
    located_in trans-Golgi network transport vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in transport vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026697.4NP_080973.1  ras-related protein Rab-14

      See identical proteins and their annotated locations for NP_080973.1

      Status: VALIDATED

      Source sequence(s)
      AL773523
      Consensus CDS
      CCDS15959.1
      UniProtKB/Swiss-Prot
      Q91V41
      UniProtKB/TrEMBL
      Q50HX4
      Related
      ENSMUSP00000028238.9, ENSMUST00000028238.15
      Conserved Domains (1) summary
      cd04122
      Location:10175
      Rab14; Rab GTPase family 14 (Rab14)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      35070217..35091132 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036162516.1XP_036018409.1  ras-related protein Rab-14 isoform X1

      Conserved Domains (1) summary
      cl38936
      Location:10157
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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