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    S100a6 S100 calcium binding protein A6 (calcyclin) [ Mus musculus (house mouse) ]

    Gene ID: 20200, updated on 23-Jun-2021

    Summary

    Official Symbol
    S100a6provided by MGI
    Official Full Name
    S100 calcium binding protein A6 (calcyclin)provided by MGI
    Primary source
    MGI:MGI:1339467
    See related
    Ensembl:ENSMUSG00000001025
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2A; 2A9; Cac; PRA; 5B10; CALC; Cacy; CALCYCLIN
    Expression
    Biased expression in bladder adult (RPKM 1598.0), colon adult (RPKM 575.5) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See S100a6 in Genome Data Viewer
    Location:
    3 F1; 3 39.35 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (90520201..90521721)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (90612894..90614414)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (90416816..90418336)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene S100 calcium binding protein A4 Neighboring gene S100 calcium binding protein A5 Neighboring gene predicted gene, 19739 Neighboring gene S100 calcium binding protein A7A

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables S100 protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables S100 protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables calcium ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables calcium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables calcium-dependent protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables calcium-dependent protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ion transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables tropomyosin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix HDA PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extrinsic component of cytoplasmic side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in perinuclear region of cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ruffle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein S100-A6
    Names
    S100 calcium-binding protein A6
    calcium binding protein A6 (calcyclin)
    prolactin receptor-associated protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011313.2NP_035443.1  protein S100-A6

      See identical proteins and their annotated locations for NP_035443.1

      Status: VALIDATED

      Source sequence(s)
      AK008941, BM932500
      Consensus CDS
      CCDS38506.1
      UniProtKB/Swiss-Prot
      P14069
      UniProtKB/TrEMBL
      Q545I9
      Related
      ENSMUSP00000001051.5, ENSMUST00000001051.9
      Conserved Domains (1) summary
      cd05029
      Location:188
      S-100A6; S-100A6 domain found in proteins similar to S100A6. S100A6 is a member of the S100 domain family within EF-hand Ca2+-binding proteins superfamily. Note that the S-100 hierarchy, to which this S-100A6 group belongs, contains only S-100 EF-hand domains, ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      90520201..90521721
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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