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Puf60 poly-U binding splicing factor 60 [ Rattus norvegicus (Norway rat) ]

Gene ID: 84401, updated on 5-Sep-2021

Summary

Official Symbol
Puf60provided by RGD
Official Full Name
poly-U binding splicing factor 60provided by RGD
Primary source
RGD:621674
See related
Ensembl:ENSRNOG00000009960
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Siahbp1
Summary
RNA-binding protein [RGD, Feb 2006]
Expression
Biased expression in Heart (RPKM 267.2), Thymus (RPKM 260.1) and 9 other tissues See more
Orthologs
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Genomic context

See Puf60 in Genome Data Viewer
Location:
7q34
Exon count:
13
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (107782770..107793814, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (117129237..117140234, complement)

Chromosome 7 - NC_051342.1Genomic Context describing neighboring genes Neighboring gene IQ motif and ankyrin repeat containing 1 Neighboring gene scribble planar cell polarity protein Neighboring gene uncharacterized LOC102548315 Neighboring gene nuclear receptor binding protein 2 Neighboring gene epiplakin 1 Neighboring gene similar to dystonin isoform 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in RNA splicing IEA
Inferred from Electronic Annotation
more info
 
involved_in alternative mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA splice site selection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of alternative mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of alternative mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 
located_in cell junction ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
poly(U)-binding-splicing factor PUF60
Names
60 kDa poly(U)-binding-splicing factor
FBP interacting repressor
RNA-binding protein Siah-BP
Ro ribonucleoprotein-binding protein 1
poly-U binding splicing factor 60K
pyrimidine tract binding splicing factor
siah binding protein 1; FBP interacting repressor; pyrimidine tract binding splicing factor; Ro ribonucleoprotein-binding protein 1
siah-binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191880.1NP_001178809.1  poly(U)-binding-splicing factor PUF60

    See identical proteins and their annotated locations for NP_001178809.1

    Status: PROVISIONAL

    Source sequence(s)
    JACYVU010000186
    UniProtKB/TrEMBL
    A0A0H2UHZ6
    Related
    ENSRNOP00000053317.3, ENSRNOT00000056481.5
    Conserved Domains (1) summary
    TIGR01645
    Location:9563
    half-pint; poly-U binding splicing factor, half-pint family

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051342.1 Reference mRatBN7.2 Primary Assembly

    Range
    107782770..107793814 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006241894.4XP_006241956.2  poly(U)-binding-splicing factor PUF60 isoform X1

    UniProtKB/Swiss-Prot
    Q9WV25
    Conserved Domains (1) summary
    TIGR01645
    Location:7564
    half-pint; poly-U binding splicing factor, half-pint family
  2. XM_006241895.4XP_006241957.2  poly(U)-binding-splicing factor PUF60 isoform X2

    UniProtKB/Swiss-Prot
    Q9WV25
    Related
    ENSRNOP00000013353.4
    Conserved Domains (1) summary
    TIGR01645
    Location:7547
    half-pint; poly-U binding splicing factor, half-pint family
  3. XM_006241896.4XP_006241958.2  poly(U)-binding-splicing factor PUF60 isoform X3

    Conserved Domains (1) summary
    TIGR01645
    Location:9546
    half-pint; poly-U binding splicing factor, half-pint family
  4. XM_006241898.4XP_006241960.2  poly(U)-binding-splicing factor PUF60 isoform X5

    Conserved Domains (1) summary
    TIGR01645
    Location:9513
    half-pint; poly-U binding splicing factor, half-pint family
  5. XM_006241897.4XP_006241959.2  poly(U)-binding-splicing factor PUF60 isoform X4

    Conserved Domains (1) summary
    TIGR01645
    Location:9530
    half-pint; poly-U binding splicing factor, half-pint family
  6. XM_039079983.1XP_038935911.1  poly(U)-binding-splicing factor PUF60 isoform X6

    Conserved Domains (1) summary
    TIGR01645
    Location:2557
    half-pint; poly-U binding splicing factor, half-pint family
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