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Lin37 lin-37 DREAM MuvB core complex component [ Mus musculus (house mouse) ]

Gene ID: 75660, updated on 23-Jun-2021

Summary

Official Symbol
Lin37provided by MGI
Official Full Name
lin-37 DREAM MuvB core complex componentprovided by MGI
Primary source
MGI:MGI:1922910
See related
Ensembl:ENSMUSG00000036845
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1810054G18Rik
Expression
Ubiquitous expression in thymus adult (RPKM 17.2), adrenal adult (RPKM 16.1) and 28 other tissues See more
Orthologs
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Genomic context

See Lin37 in Genome Data Viewer
Location:
7; 7 B1
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (30254866..30259289, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (30555441..30559721, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (31340460..31344665, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene proline and serine rich 3 Neighboring gene microRNA 9769 Neighboring gene heat shock protein, alpha-crystallin-related, B6 Neighboring gene presenilin enhancer gamma secretase subunit Neighboring gene U2 small nuclear RNA auxiliary factor 1-like 4 Neighboring gene IGF-like family receptor 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of Myb complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of transcription repressor complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein lin-37 homolog
Names
antolefinin
antolefinine
lin-37 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290569.1NP_001277498.1  protein lin-37 homolog isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice junction at the 5' end of an exon and intiates translation at a downstream AUG compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AC167970, AK007858, BY707863
    Consensus CDS
    CCDS71930.1
    UniProtKB/Swiss-Prot
    Q9D8N6
    UniProtKB/TrEMBL
    E9Q0Q9
    Related
    ENSMUSP00000103799.2, ENSMUST00000108164.8
    Conserved Domains (1) summary
    pfam15306
    Location:72228
    LIN37; LIN37
  2. NM_029377.2NP_083653.1  protein lin-37 homolog isoform 1

    See identical proteins and their annotated locations for NP_083653.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK007858
    Consensus CDS
    CCDS21098.1
    UniProtKB/Swiss-Prot
    Q9D8N6
    Related
    ENSMUSP00000048557.5, ENSMUST00000043975.11
    Conserved Domains (1) summary
    pfam15306
    Location:84240
    LIN37; LIN37

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    30254866..30259289 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011250734.4XP_011249036.1  protein lin-37 homolog isoform X1

    Conserved Domains (1) summary
    pfam15306
    Location:95251
    LIN37
  2. XM_036153535.1XP_036009428.1  protein lin-37 homolog isoform X3

    Conserved Domains (1) summary
    pfam15306
    Location:5161
    LIN37
  3. XM_017312369.3XP_017167858.1  protein lin-37 homolog isoform X2

    Conserved Domains (1) summary
    pfam15306
    Location:83239
    LIN37
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