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Zkscan3 zinc finger with KRAB and SCAN domains 3 [ Mus musculus (house mouse) ]

Gene ID: 72739, updated on 6-May-2021

Summary

Official Symbol
Zkscan3provided by MGI
Official Full Name
zinc finger with KRAB and SCAN domains 3provided by MGI
Primary source
MGI:MGI:1919989
See related
Ensembl:ENSMUSG00000021327
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Skz; Skz1; Zf47; Zfp30; Zfp-47; Zfp306; Zfp307; mszf35; AA408594; AI132359; 2810435N07Rik
Expression
Ubiquitous expression in CNS E11.5 (RPKM 18.0), limb E14.5 (RPKM 16.1) and 28 other tissues See more
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Genomic context

See Zkscan3 in Genome Data Viewer
Location:
13; 13 A3.1
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (21571174..21586942, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (21387004..21402755, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (21478873..21494624, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor 1367 Neighboring gene zinc finger and SCAN domain containing 12 Neighboring gene microRNA 6942 Neighboring gene piggyBac transposable element derived 1 Neighboring gene RIKEN cDNA 4930470G03 gene Neighboring gene zinc finger and SCAN domain containing 26 Neighboring gene microRNA 1896

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
zinc finger protein with KRAB and SCAN domains 3
Names
SCAN-KRAB-zinc finger gene 1
SCAN-KRAB-zinc finger protein
zinc finger protein 306
zinc finger protein 307
zinc finger protein 47 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145778.2NP_001139250.1  zinc finger protein with KRAB and SCAN domains 3 isoform a

    See identical proteins and their annotated locations for NP_001139250.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AI132359, AK028902, AK031286, BX001068
    Consensus CDS
    CCDS26274.1
    UniProtKB/Swiss-Prot
    Q91VW9
    UniProtKB/TrEMBL
    A0A0R4J1L3
    Related
    ENSMUSP00000068424.9, ENSMUST00000070785.16
    Conserved Domains (6) summary
    smart00431
    Location:47159
    SCAN; leucine rich region
    COG5048
    Location:367514
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:371391
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:328350
    zf-H2C2_2; Zinc-finger double domain
    cl02581
    Location:213267
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  2. NM_001368182.1NP_001355111.1  zinc finger protein with KRAB and SCAN domains 3 isoform b

    Status: VALIDATED

    Source sequence(s)
    AI132359, AK028902, BX001068, CK627138
    Consensus CDS
    CCDS88419.1
    Related
    ENSMUSP00000153241.2, ENSMUST00000223831.2
  3. NM_023685.5NP_076174.3  zinc finger protein with KRAB and SCAN domains 3 isoform a

    See identical proteins and their annotated locations for NP_076174.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses a different splice site in the 5' UTR, compared to variant 1. Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AI132359, AK028902, BX001068
    Consensus CDS
    CCDS26274.1
    UniProtKB/Swiss-Prot
    Q91VW9
    UniProtKB/TrEMBL
    A0A0R4J1L3
    Related
    ENSMUSP00000112135.4, ENSMUST00000116434.11
    Conserved Domains (6) summary
    smart00431
    Location:47159
    SCAN; leucine rich region
    COG5048
    Location:367514
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:371391
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:328350
    zf-H2C2_2; Zinc-finger double domain
    cl02581
    Location:213267
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    21571174..21586942 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516790.5XP_006516853.1  zinc finger protein with KRAB and SCAN domains 3 isoform X1

    See identical proteins and their annotated locations for XP_006516853.1

    UniProtKB/Swiss-Prot
    Q91VW9
    UniProtKB/TrEMBL
    A0A0R4J1L3
    Conserved Domains (6) summary
    smart00431
    Location:47159
    SCAN; leucine rich region
    COG5048
    Location:367514
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:371391
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:328350
    zf-H2C2_2; Zinc-finger double domain
    cl02581
    Location:213267
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  2. XM_006516789.5XP_006516852.1  zinc finger protein with KRAB and SCAN domains 3 isoform X1

    See identical proteins and their annotated locations for XP_006516852.1

    UniProtKB/Swiss-Prot
    Q91VW9
    UniProtKB/TrEMBL
    A0A0R4J1L3
    Conserved Domains (6) summary
    smart00431
    Location:47159
    SCAN; leucine rich region
    COG5048
    Location:367514
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:371391
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:328350
    zf-H2C2_2; Zinc-finger double domain
    cl02581
    Location:213267
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  3. XM_006516792.4XP_006516855.1  zinc finger protein with KRAB and SCAN domains 3 isoform X2

    Conserved Domains (4) summary
    COG5048
    Location:113260
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:117137
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:253275
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:7496
    zf-H2C2_2; Zinc-finger double domain
  4. XM_036158185.1XP_036014078.1  zinc finger protein with KRAB and SCAN domains 3 isoform X3

    Conserved Domains (2) summary
    smart00431
    Location:47159
    SCAN; leucine rich region
    cl02581
    Location:213251
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  5. XM_036158186.1XP_036014079.1  zinc finger protein with KRAB and SCAN domains 3 isoform X3

    Related
    ENSMUSP00000112134.2, ENSMUST00000116433.2
    Conserved Domains (2) summary
    smart00431
    Location:47159
    SCAN; leucine rich region
    cl02581
    Location:213251
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  6. XM_036158187.1XP_036014080.1  zinc finger protein with KRAB and SCAN domains 3 isoform X3

    Related
    ENSMUSP00000112862.2, ENSMUST00000117721.8
    Conserved Domains (2) summary
    smart00431
    Location:47159
    SCAN; leucine rich region
    cl02581
    Location:213251
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
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