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Mfsd8 major facilitator superfamily domain containing 8 [ Mus musculus (house mouse) ]

Gene ID: 72175, updated on 23-Jun-2021

Summary

Official Symbol
Mfsd8provided by MGI
Official Full Name
major facilitator superfamily domain containing 8provided by MGI
Primary source
MGI:MGI:1919425
See related
Ensembl:ENSMUSG00000025759
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cl; Cln7; AI836898; AV142426; 2810423E13Rik
Expression
Ubiquitous expression in subcutaneous fat pad adult (RPKM 4.3), CNS E18 (RPKM 4.2) and 27 other tissues See more
Orthologs
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Genomic context

See Mfsd8 in Genome Data Viewer
Location:
3; 3 B
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (40772500..40801322, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (40818065..40846880, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (40622094..40650776, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene heat shock protein 4 like Neighboring gene polo like kinase 4 Neighboring gene predicted gene 2011 Neighboring gene FUN14 domain containing 2 pseudogene Neighboring gene RIKEN cDNA 6430590A07 gene Neighboring gene abhydrolase domain containing 18

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Clone Names

  • MGC132949, MGC132950

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in lysosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
major facilitator superfamily domain-containing protein 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028140.5NP_082416.2  major facilitator superfamily domain-containing protein 8

    See identical proteins and their annotated locations for NP_082416.2

    Status: VALIDATED

    Source sequence(s)
    AC160757
    Consensus CDS
    CCDS17329.1
    UniProtKB/Swiss-Prot
    Q8BH31
    Related
    ENSMUSP00000026859.6, ENSMUST00000026859.11
    Conserved Domains (2) summary
    cd06174
    Location:40504
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:43470
    MFS_1; Major Facilitator Superfamily

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    40772500..40801322 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036163349.1XP_036019242.1  major facilitator superfamily domain-containing protein 8 isoform X1

    Conserved Domains (1) summary
    cd17326
    Location:1373
    MFS_MFSD8; Major facilitator superfamily domain-containing protein 8

RNA

  1. XR_004941405.1 RNA Sequence

  2. XR_004941404.1 RNA Sequence

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