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TMPRSS2 transmembrane serine protease 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 715138, updated on 24-Jun-2020

Summary

Official Symbol
TMPRSS2provided by VGNC
Official Full Name
transmembrane serine protease 2provided by VGNC
Primary source
VGNC:VGNC:78575
See related
Ensembl:ENSMMUG00000015332
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

See TMPRSS2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
16
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (5139757..5184755)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (5176312..5217342)

Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene small nucleolar RNA SNORA32 Neighboring gene MX dynamin like GTPase 1 Neighboring gene MX dynamin like GTPase 2 Neighboring gene uncharacterized LOC114676800

Genomic regions, transcripts, and products

General gene information

Markers

Homology

General protein information

Preferred Names
transmembrane protease serine 2
Names
transmembrane protease, serine 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041756.1 Reference Mmul_10 Primary Assembly

    Range
    5139757..5184755
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028845315.1XP_028701148.1  transmembrane protease serine 2 isoform X1

    Conserved Domains (3) summary
    cd00112
    Location:155190
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:298529
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:195290
    SRCR_2; Scavenger receptor cysteine-rich domain
  2. XM_015132845.2XP_014988331.1  transmembrane protease serine 2 isoform X3

    UniProtKB/TrEMBL
    A0A1D5RIR7
    Related
    ENSMMUP00000060211.1, ENSMMUT00000072841.2
    Conserved Domains (5) summary
    smart00020
    Location:255484
    Tryp_SPc; Trypsin-like serine protease
    cd00112
    Location:113148
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:256487
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam12868
    Location:754
    DUF3824; Domain of unknwon function (DUF3824)
    pfam15494
    Location:153248
    SRCR_2; Scavenger receptor cysteine-rich domain
  3. XM_028845316.1XP_028701149.1  transmembrane protease serine 2 isoform X2

    Related
    ENSMMUP00000068248.1, ENSMMUT00000093883.1
    Conserved Domains (3) summary
    cd00112
    Location:146181
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:289520
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:186281
    SRCR_2; Scavenger receptor cysteine-rich domain
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