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Polr2e RNA polymerase II, I and III subunit E [ Rattus norvegicus (Norway rat) ]

Gene ID: 690966, updated on 6-May-2021

Summary

Official Symbol
Polr2eprovided by RGD
Official Full Name
RNA polymerase II, I and III subunit Eprovided by RGD
Primary source
RGD:1589817
See related
Ensembl:ENSRNOG00000013545
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Adrenal (RPKM 343.5), Kidney (RPKM 301.6) and 9 other tissues See more
Orthologs
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Genomic context

See Polr2e in Genome Data Viewer
Location:
7q11
Exon count:
6
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (9666695..9670638)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (12532785..12536797)

Chromosome 7 - NC_051342.1Genomic Context describing neighboring genes Neighboring gene strawberry notch homolog 2 Neighboring gene glutathione peroxidase 4 Neighboring gene Rho GTPase activating protein 45 Neighboring gene ATP binding cassette subfamily A member 7

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to DNA-directed 5'-3' RNA polymerase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of RNA polymerase I complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of RNA polymerase II, core complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of RNA polymerase II, core complex ISO
Inferred from Sequence Orthology
more info
 
part_of RNA polymerase II, core complex ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of RNA polymerase III complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cellular_component ND
No biological Data available
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
DNA-directed RNA polymerases I, II, and III subunit RPABC1
Names
DNA-directed RNA polymerase II subunit E
RNA polymerase II subunit E
RNA polymerases I, II, and III subunit ABC1
RPB5 homolog
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
polymerase (RNA) II subunit E
NP_001103084.1
XP_006241071.1
XP_006241072.1
XP_006241073.1
XP_038935858.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109614.1NP_001103084.1  DNA-directed RNA polymerases I, II, and III subunit RPABC1

    See identical proteins and their annotated locations for NP_001103084.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474029
    UniProtKB/Swiss-Prot
    B0BNE2
    Related
    ENSRNOP00000018169.4, ENSRNOT00000018169.5
    Conserved Domains (1) summary
    PLN03111
    Location:1209
    PLN03111; DNA-directed RNA polymerase II subunit family protein; Provisional

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051342.1 Reference mRatBN7.2 Primary Assembly

    Range
    9666695..9670638
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039079930.1XP_038935858.1  DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X3

    Conserved Domains (1) summary
    PLN03111
    Location:1209
    PLN03111; DNA-directed RNA polymerase II subunit family protein; Provisional
  2. XM_006241009.4XP_006241071.1  DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1

    See identical proteins and their annotated locations for XP_006241071.1

    Conserved Domains (3) summary
    PLN03111
    Location:1190
    PLN03111; DNA-directed RNA polymerase II subunit family protein; Provisional
    pfam01191
    Location:138190
    RNA_pol_Rpb5_C; RNA polymerase Rpb5, C-terminal domain
    pfam03871
    Location:492
    RNA_pol_Rpb5_N; RNA polymerase Rpb5, N-terminal domain
  3. XM_006241010.2XP_006241072.1  DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X2

    Conserved Domains (2) summary
    pfam01191
    Location:130182
    RNA_pol_Rpb5_C; RNA polymerase Rpb5, C-terminal domain
    pfam03871
    Location:1184
    RNA_pol_Rpb5_N; RNA polymerase Rpb5, N-terminal domain
  4. XM_006241011.2XP_006241073.1  DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X4

    See identical proteins and their annotated locations for XP_006241073.1

    UniProtKB/TrEMBL
    A0A1W2Q690
    Related
    ENSRNOP00000076166.1
    Conserved Domains (3) summary
    PLN03111
    Location:15201
    PLN03111; DNA-directed RNA polymerase II subunit family protein; Provisional
    pfam01191
    Location:130201
    RNA_pol_Rpb5_C; RNA polymerase Rpb5, C-terminal domain
    pfam03871
    Location:1184
    RNA_pol_Rpb5_N; RNA polymerase Rpb5, N-terminal domain
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