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Pnisr PNN interacting serine/arginine-rich [ Mus musculus (house mouse) ]

Gene ID: 66625, updated on 23-Jun-2021

Summary

Official Symbol
Pnisrprovided by MGI
Official Full Name
PNN interacting serine/arginine-richprovided by MGI
Primary source
MGI:MGI:1913875
See related
Ensembl:ENSMUSG00000028248
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sfr; Pinsr; Sfrs18; Srsf18; AA673174; 5730406M06Rik
Expression
Broad expression in CNS E11.5 (RPKM 36.1), CNS E14 (RPKM 33.4) and 24 other tissues See more
Orthologs
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Genomic context

See Pnisr in Genome Data Viewer
Location:
4; 4 A3
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (21846621..21876475)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (21846657..21876475)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (21774730..21803622)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene cyclin C Neighboring gene thiosulfate sulfurtransferase (rhodanese)-like domain containing 3 Neighboring gene ubiquitin specific petidase 45 Neighboring gene RIKEN cDNA 4930528A17 gene Neighboring gene coenzyme Q3 methyltransferase Neighboring gene failed axon connections homolog

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in nuclear speck IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in presynaptic active zone IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
arginine/serine-rich protein PNISR
Names
SRrp130
serine/arginine-rich splicing factor 18
serine/arginine-rich-splicing regulatory protein 130
splicing factor, arginine/serine-rich 130
splicing factor, arginine/serine-rich 18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001369189.1NP_001356118.1  arginine/serine-rich protein PNISR isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL772187
    Consensus CDS
    CCDS89720.1
    Related
    ENSMUSP00000095840.3, ENSMUST00000098238.9
    Conserved Domains (2) summary
    TIGR01642
    Location:643750
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam15996
    Location:223380
    PNISR; Arginine/serine-rich protein PNISR
  2. NM_001369190.1NP_001356119.1  arginine/serine-rich protein PNISR isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL772187
    Conserved Domains (2) summary
    TIGR01642
    Location:401508
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam15996
    Location:1138
    PNISR; Arginine/serine-rich protein PNISR
  3. NM_001369191.1NP_001356120.1  arginine/serine-rich protein PNISR isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL772187
    Conserved Domains (2) summary
    TIGR01642
    Location:401508
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam15996
    Location:1138
    PNISR; Arginine/serine-rich protein PNISR
  4. NM_025669.2NP_079945.1  arginine/serine-rich protein PNISR isoform 1

    See identical proteins and their annotated locations for NP_079945.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AL772187
    Consensus CDS
    CCDS51129.1
    UniProtKB/TrEMBL
    A2AJT5
    Related
    ENSMUSP00000029911.6, ENSMUST00000029911.12
    Conserved Domains (2) summary
    TIGR01642
    Location:643750
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam15996
    Location:223380
    PNISR; Arginine/serine-rich protein PNISR

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    21846621..21876475
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017320353.3XP_017175842.1  arginine/serine-rich protein PNISR isoform X3

  2. XM_030253702.2XP_030109562.1  arginine/serine-rich protein PNISR isoform X2

    Conserved Domains (2) summary
    TIGR01642
    Location:548655
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam15996
    Location:128285
    PNISR; Arginine/serine-rich protein PNISR
  3. XM_006538184.5XP_006538247.1  arginine/serine-rich protein PNISR isoform X1

    See identical proteins and their annotated locations for XP_006538247.1

    UniProtKB/TrEMBL
    A2AJT5
    Conserved Domains (2) summary
    TIGR01642
    Location:643750
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam15996
    Location:223380
    PNISR; Arginine/serine-rich protein PNISR
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