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Copb2 COPI coat complex subunit beta 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 60384, updated on 24-Jul-2021

Summary

Official Symbol
Copb2provided by RGD
Official Full Name
COPI coat complex subunit beta 2provided by RGD
Primary source
RGD:628746
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
p102; Rack2
Summary
acts as a receptor for activated protein kinase C epsilon; may play a role in vesicle mediated transport [RGD, Feb 2006]
Expression
Biased expression in Kidney (RPKM 421.2), Liver (RPKM 417.4) and 9 other tissues See more
Orthologs
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Genomic context

See Copb2 in Genome Data Viewer
Location:
8q31
Exon count:
22
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (99161324..99183452)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (106582339..106603763)

Chromosome 8 - NC_051343.1Genomic Context describing neighboring genes Neighboring gene retinol binding protein 2 Neighboring gene similar to Nucleoside diphosphate kinase B (NDK B) (NDP kinase B) (P18) Neighboring gene mitochondrial ribosomal protein S22 Neighboring gene proline rich 23A

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC93460

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein kinase C binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in intra-Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in intra-Golgi vesicle-mediated transport ISO
Inferred from Sequence Orthology
more info
 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within toxin transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of COPI vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of COPI vesicle coat ISO
Inferred from Sequence Orthology
more info
 
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in Golgi membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in exocytic vesicle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
coatomer subunit beta'
Names
beta prime COP
beta'-COP
beta'-coat protein
coatomer protein complex subunit beta 2
coatomer protein complex, subunit beta 2 (beta prime)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021765.2NP_068533.2  coatomer subunit beta'

    Status: PROVISIONAL

    Source sequence(s)
    JACYVU010000200
    Conserved Domains (3) summary
    cd00200
    Location:8297
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:103140
    7WD40; WD40 repeat [structural motif]
    pfam04053
    Location:319763
    Coatomer_WDAD; Coatomer WD associated region

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051343.1 Reference mRatBN7.2 Primary Assembly

    Range
    99161324..99183452
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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