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Klrc3 killer cell lectin like receptor C3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 500338, updated on 12-Jan-2022

Summary

Official Symbol
Klrc3provided by RGD
Official Full Name
killer cell lectin like receptor C3provided by RGD
Primary source
RGD:1560637
See related
Ensembl:ENSRNOG00000065970
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in positive regulation of natural killer cell mediated cytotoxicity and stimulatory C-type lectin receptor signaling pathway. Predicted to be active in external side of plasma membrane. Predicted to be integral component of plasma membrane. Orthologous to human KLRC3 (killer cell lectin like receptor C3). [provided by Alliance of Genome Resources, Nov 2021]
Expression
Biased expression in Spleen (RPKM 75.1), Thymus (RPKM 41.4) and 7 other tissues See more
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Genomic context

See Klrc3 in Genome Data Viewer
Location:
4q42
Exon count:
7
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (163105081..163112737, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (163416373..163427331, complement)

Chromosome 4 - NC_051339.1Genomic Context describing neighboring genes Neighboring gene killer cell lectin like receptor D1 Neighboring gene killer cell lectin like receptor K1 Neighboring gene killer cell lectin like receptor C2 Neighboring gene killer cell lectin like receptor C1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
killer cell lectin like receptor C3
Names
killer cell lectin-like receptor subfamily C, member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001029908.1NP_001025079.1  killer cell lectin like receptor C3

    See identical proteins and their annotated locations for NP_001025079.1

    Status: PROVISIONAL

    Source sequence(s)
    JACYVU010000150
    UniProtKB/TrEMBL
    Q6XZ77
    Conserved Domains (1) summary
    cd03593
    Location:114226
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051339.1 Reference mRatBN7.2 Primary Assembly

    Range
    163105081..163112737 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008763324.3XP_008761546.1  killer cell lectin like receptor C3 isoform X1

    See identical proteins and their annotated locations for XP_008761546.1

    UniProtKB/TrEMBL
    Q6XZ77
    Related
    ENSRNOP00000073530.2, ENSRNOT00000087106.2
    Conserved Domains (1) summary
    cd03593
    Location:114226
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
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