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tmprss2 transmembrane serine protease 2 [ Danio rerio (zebrafish) ]

Gene ID: 494080, updated on 6-May-2021

Summary

Official Symbol
tmprss2provided by ZNC
Official Full Name
transmembrane serine protease 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-041212-48
See related
Ensembl:ENSDARG00000098686
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:101791
Annotation information
Annotation category: partial on reference assembly
Orthologs
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Genomic context

See tmprss2 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (38707839..38729673)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (38764432..38786266)
103 previous assembly Zv9 (GCF_000002035.4) 10 NC_007121.5 (39993725..40016124, complement)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene matrix metallopeptidase 30 Neighboring gene acetyl-CoA acetyltransferase 1 Neighboring gene uncharacterized LOC103911777 Neighboring gene Down syndrome cell adhesion molecule a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables serine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane protease serine 2
Names
transmembrane protease, serine 2
NP_001008623.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008623.1NP_001008623.1  transmembrane protease serine 2

    See identical proteins and their annotated locations for NP_001008623.1

    Status: PROVISIONAL

    Source sequence(s)
    BC086738
    UniProtKB/TrEMBL
    Q5PRA6
    Related
    ENSDARP00000134497.1, ENSDART00000172306.2
    Conserved Domains (4) summary
    smart00020
    Location:251479
    Tryp_SPc; Trypsin-like serine protease
    cd00112
    Location:132168
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:252482
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    cl02509
    Location:173248
    SRCR_2; Scavenger receptor cysteine-rich domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    38707839..38729673
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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