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TMPRSS2 transmembrane serine protease 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 474007, updated on 19-Mar-2021

Summary

Official Symbol
TMPRSS2provided by VGNC
Official Full Name
transmembrane serine protease 2provided by VGNC
Primary source
VGNC:VGNC:3729
Locus tag
CK820_G0022846
See related
Ensembl:ENSPTRG00000013928
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

See TMPRSS2 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
14
Annotation release Status Assembly Chr Location
105 current Clint_PTRv2 (GCF_002880755.1) 21 NC_036900.1 (28002808..28046474, complement)
104 previous assembly Pan_tro 3.0 (GCF_000001515.7) 21 NC_006488.4 (27971275..28016503, complement)

Chromosome 21 - NC_036900.1Genomic Context describing neighboring genes Neighboring gene MX dynamin like GTPase 2 Neighboring gene MX dynamin like GTPase 1 Neighboring gene small nucleolar RNA SNORA32 Neighboring gene small nucleolar RNA U13

Genomic regions, transcripts, and products

General gene information

Markers

Homology

General protein information

Preferred Names
transmembrane protease serine 2
Names
transmembrane protease, serine 2
XP_001172064.4
XP_016794054.1
XP_016794055.1
XP_024208115.1
XP_024208116.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pan troglodytes Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Clint_PTRv2 Primary Assembly

Genomic

  1. NC_036900.1 Reference Clint_PTRv2 Primary Assembly

    Range
    28002808..28046474 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016938566.2XP_016794055.1  transmembrane protease serine 2 isoform X5

  2. XM_016938565.2XP_016794054.1  transmembrane protease serine 2 isoform X2

    UniProtKB/TrEMBL
    H2QL19
    Conserved Domains (3) summary
    cd00112
    Location:113148
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:256487
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:153246
    SRCR_2; Scavenger receptor cysteine-rich domain
  3. XM_024352348.1XP_024208116.1  transmembrane protease serine 2 isoform X4

    Conserved Domains (2) summary
    cd00190
    Location:224455
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:121214
    SRCR_2; Scavenger receptor cysteine-rich domain
  4. XM_024352347.1XP_024208115.1  transmembrane protease serine 2 isoform X3

    Conserved Domains (2) summary
    cd00190
    Location:253484
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:150243
    SRCR_2; Scavenger receptor cysteine-rich domain
  5. XM_001172064.5XP_001172064.4  transmembrane protease serine 2 isoform X1

    Conserved Domains (3) summary
    cd00112
    Location:150185
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:293524
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:190283
    SRCR_2; Scavenger receptor cysteine-rich domain
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