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TMPRSS2 transmembrane protease, serine 2 [ Gallus gallus (chicken) ]

Gene ID: 418528, updated on 7-Aug-2021

Summary

Symbol
TMPRSS2provided by CGNC
Full Name
transmembrane protease, serine 2provided by CGNC
Primary source
CGNC:12069
See related
Ensembl:ENSGALG00000016144
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
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Genomic context

See TMPRSS2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
17
Annotation release Status Assembly Chr Location
105 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (109023600..109044131, complement)
105 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.1) 1 NC_052573.1 (109107185..109128059, complement)
104 previous assembly GRCg6a (GCF_000002315.5) 1 NC_006088.5 (110261647..110282528, complement)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 1 NC_006088.4 (108943153..108964045, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 3 member B Neighboring gene myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) Neighboring gene uncharacterized LOC107056158 Neighboring gene uncharacterized LOC101751349 Neighboring gene receptor interacting serine/threonine kinase 4

Genomic regions, transcripts, and products

General gene information

Homology

General protein information

Preferred Names
transmembrane protease serine 2
Names
transmembrane serine protease 2
XP_015156666.1
XP_040508208.1
XP_040515615.1
XP_040515616.1
XP_040515617.1
XP_416737.4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    109023600..109044131 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_416737.7XP_416737.4  transmembrane protease serine 2

    UniProtKB/TrEMBL
    F1NY88
    Related
    ENSGALP00000025956.4
    Conserved Domains (3) summary
    cd00112
    Location:105140
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:250481
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:145241
    SRCR_2; Scavenger receptor cysteine-rich domain
  2. XM_015301180.3XP_015156666.1  transmembrane protease serine 2

    UniProtKB/TrEMBL
    F1NY88
    Conserved Domains (3) summary
    cd00112
    Location:105140
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:250481
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:145241
    SRCR_2; Scavenger receptor cysteine-rich domain
  3. XM_040652274.1XP_040508208.1  transmembrane protease serine 2

    Conserved Domains (3) summary
    cd00112
    Location:105140
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:250481
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:145241
    SRCR_2; Scavenger receptor cysteine-rich domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    109107185..109128059 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040659681.1XP_040515615.1  transmembrane protease serine 2

    Conserved Domains (3) summary
    cd00112
    Location:105140
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:250481
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:145241
    SRCR_2; Scavenger receptor cysteine-rich domain
  2. XM_040659682.1XP_040515616.1  transmembrane protease serine 2

    Conserved Domains (3) summary
    cd00112
    Location:105140
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:250481
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:145241
    SRCR_2; Scavenger receptor cysteine-rich domain
  3. XM_040659683.1XP_040515617.1  transmembrane protease serine 2

    Conserved Domains (3) summary
    cd00112
    Location:105140
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:250481
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:145241
    SRCR_2; Scavenger receptor cysteine-rich domain
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