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Gdi2 GDP dissociation inhibitor 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 29662, updated on 22-Aug-2021

Summary

Official Symbol
Gdi2provided by RGD
Official Full Name
GDP dissociation inhibitor 2provided by RGD
Primary source
RGD:61802
See related
Ensembl:ENSRNOG00000018091
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Gdi3
Summary
regulatory protein for GDP/GTP exchange reaction of Rab proteins; mediates vesicular trafficking in diverse types of cells [RGD, Feb 2006]
Expression
Biased expression in Kidney (RPKM 1141.8), Spleen (RPKM 1135.1) and 9 other tissues See more
Orthologs
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Genomic context

See Gdi2 in Genome Data Viewer
Location:
17q12.2
Exon count:
11
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (66649616..66676299, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (70299177..70325864, complement)

Chromosome 17 - NC_051352.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L29, pseudogene 3 Neighboring gene ankyrin repeat and SOCS box-containing 13 Neighboring gene transcription activation suppressor family member 2 Neighboring gene uncharacterized LOC120097798 Neighboring gene uncharacterized LOC120097902

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
contributes_to GTPase activator activity ISO
Inferred from Sequence Orthology
more info
 
enables Rab GDP-dissociation inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables Rab GDP-dissociation inhibitor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables small GTPase binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in protein transport TAS
Traceable Author Statement
more info
PubMed 
involved_in regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within small GTPase mediated signal transduction ISO
Inferred from Sequence Orthology
more info
 
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in vesicle-mediated transport IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in synapse EXP
Inferred from Experiment
more info
PubMed 
located_in synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
rab GDP dissociation inhibitor beta
Names
GDI-2
GDI-3
guanosine diphosphate (GDP) dissociation inhibitor 3
guanosine diphosphate dissociation inhibitor 2
guanosine diphosphate dissociation inhibitor 3
rab GDI beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017276.2NP_058972.2  rab GDP dissociation inhibitor beta

    See identical proteins and their annotated locations for NP_058972.2

    Status: PROVISIONAL

    Source sequence(s)
    BC061767
    UniProtKB/Swiss-Prot
    P50399
    Related
    ENSRNOP00000024952.4, ENSRNOT00000024952.6
    Conserved Domains (1) summary
    pfam00996
    Location:1436
    GDI; GDP dissociation inhibitor

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051352.1 Reference mRatBN7.2 Primary Assembly

    Range
    66649616..66676299 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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