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Rgp1 RAB6A GEF compex partner 1 [ Mus musculus (house mouse) ]

Gene ID: 242406, updated on 23-Jun-2021

Summary

Official Symbol
Rgp1provided by MGI
Official Full Name
RAB6A GEF compex partner 1provided by MGI
Primary source
MGI:MGI:1915956
See related
Ensembl:ENSMUSG00000028468
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI527196; mKIAA0258; F730001J03; 1110029E03Rik
Expression
Ubiquitous expression in thymus adult (RPKM 23.8), ovary adult (RPKM 22.3) and 28 other tissues See more
Orthologs
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Genomic context

See Rgp1 in Genome Data Viewer
Location:
4; 4 A5
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (43578735..43587487)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (43578735..43587487)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (43591607..43600359)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene talin 1 Neighboring gene cAMP responsive element binding protein 3 Neighboring gene glucosidase beta 2 Neighboring gene microseminoprotein, prostate associated Neighboring gene predicted gene, 42279 Neighboring gene natriuretic peptide receptor 2 Neighboring gene sperm associated antigen 8

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity ISO
Inferred from Sequence Orthology
more info
 
enables small GTPase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in negative regulation of cellular protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of GTPase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in retrograde transport, endosome to Golgi ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of Ric1-Rgp1 guanyl-nucleotide exchange factor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of Ric1-Rgp1 guanyl-nucleotide exchange factor complex ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
RAB6A-GEF complex partner protein 2
Names
RGP1 retrograde golgi transport homolog
retrograde Golgi transport protein RGP1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172866.3NP_766454.1  RAB6A-GEF complex partner protein 2

    See identical proteins and their annotated locations for NP_766454.1

    Status: VALIDATED

    Source sequence(s)
    AK129103, AL732626, BC086614, CJ065220
    Consensus CDS
    CCDS38741.1
    UniProtKB/Swiss-Prot
    Q8BHT7
    Related
    ENSMUSP00000103518.3, ENSMUST00000107886.9
    Conserved Domains (1) summary
    pfam08737
    Location:91331
    Rgp1

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    43578735..43587487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006537909.5XP_006537972.1  RAB6A-GEF complex partner protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006537972.1

    UniProtKB/Swiss-Prot
    Q8BHT7
    Related
    ENSMUSP00000030190.9, ENSMUST00000030190.9
    Conserved Domains (1) summary
    pfam08737
    Location:91331
    Rgp1
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