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Slc26a4 solute carrier family 26, member 4 [ Mus musculus (house mouse) ]

Gene ID: 23985, updated on 19-Jul-2021

Summary

Official Symbol
Slc26a4provided by MGI
Official Full Name
solute carrier family 26, member 4provided by MGI
Primary source
MGI:MGI:1346029
See related
Ensembl:ENSMUSG00000020651
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
P; pe; Pds; pendrin
Expression
Biased expression in kidney adult (RPKM 9.5), adrenal adult (RPKM 0.9) and 2 other tissues See more
Orthologs
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Genomic context

See Slc26a4 in Genome Data Viewer
Location:
12; 12 A2
Exon count:
22
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (31569813..31610054, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (31519814..31560055, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (32204684..32244834, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 26, member 3 Neighboring gene Casitas B-lineage lymphoma-like 1 Neighboring gene predicted gene, 40362 Neighboring gene B cell receptor associated protein 29 Neighboring gene dihydrouridine synthase 4-like (S. cerevisiae)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables anion transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables anion:anion antiporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables bicarbonate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables chloride transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables chloride transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables iodide transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables oxalate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables secondary active sulfate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables sulfate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within animal organ morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in anion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in inorganic anion transport ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of pH IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in sulfate transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in brush border membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
pendrin
Names
sodium-independent chloride/iodide transporter

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011867.4NP_035997.1  pendrin

    See identical proteins and their annotated locations for NP_035997.1

    Status: VALIDATED

    Source sequence(s)
    AC123618, CR974423
    Consensus CDS
    CCDS36429.1
    UniProtKB/Swiss-Prot
    Q9R155
    Related
    ENSMUSP00000001253.8, ENSMUST00000001253.8
    Conserved Domains (1) summary
    TIGR00815
    Location:70725
    sulP; high affinity sulphate transporter 1

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    31569813..31610054 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006515092.5XP_006515155.1  pendrin isoform X1

    See identical proteins and their annotated locations for XP_006515155.1

    UniProtKB/Swiss-Prot
    Q9R155
    Conserved Domains (1) summary
    TIGR00815
    Location:70725
    sulP; high affinity sulphate transporter 1
  2. XM_006515091.1XP_006515154.1  pendrin isoform X1

    See identical proteins and their annotated locations for XP_006515154.1

    UniProtKB/Swiss-Prot
    Q9R155
    Conserved Domains (1) summary
    TIGR00815
    Location:70725
    sulP; high affinity sulphate transporter 1
  3. XM_017315068.3XP_017170557.1  pendrin isoform X1

    UniProtKB/Swiss-Prot
    Q9R155
    Conserved Domains (1) summary
    TIGR00815
    Location:70725
    sulP; high affinity sulphate transporter 1
  4. XM_011243870.4XP_011242172.1  pendrin isoform X2

    Conserved Domains (1) summary
    pfam00916
    Location:84421
    Sulfate_transp; Sulfate permease family

RNA

  1. XR_003950047.1 RNA Sequence

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