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Srm spermidine synthase [ Mus musculus (house mouse) ]

Gene ID: 20810, updated on 23-Jun-2021

Summary

Official Symbol
Srmprovided by MGI
Official Full Name
spermidine synthaseprovided by MGI
Primary source
MGI:MGI:102690
See related
Ensembl:ENSMUSG00000006442
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sp; SpdST; SpdSy; AA407669
Expression
Ubiquitous expression in ovary adult (RPKM 69.9), limb E14.5 (RPKM 62.8) and 28 other tissues See more
Orthologs
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Genomic context

See Srm in Genome Data Viewer
Location:
4; 4 E2
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (148675970..148679076)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (148591513..148594619)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (147965622..147968728)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene mechanistic target of rapamycin kinase Neighboring gene predicted gene, 23318 Neighboring gene exosome component 10 Neighboring gene mannan-binding lectin serine peptidase 2 Neighboring gene TAR DNA binding protein Neighboring gene predicted gene 572

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the Srm gene: The Srm gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs from Annotation Pipeline: 366 organisms have orthologs with human gene Srm
  • Orthologs

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
enables spermidine synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables spermidine synthase activity ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to leukemia inhibitory factor IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in polyamine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in polyamine metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in spermidine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in spermidine biosynthetic process ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
spermidine synthase
Names
putrescine aminopropyltransferase
NP_033298.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009272.4NP_033298.1  spermidine synthase

    See identical proteins and their annotated locations for NP_033298.1

    Status: PROVISIONAL

    Source sequence(s)
    AL606969
    Consensus CDS
    CCDS18940.1
    UniProtKB/Swiss-Prot
    Q64674
    UniProtKB/TrEMBL
    Q543H0
    Related
    ENSMUSP00000006611.9, ENSMUST00000006611.9
    Conserved Domains (1) summary
    PLN02366
    Location:8298
    PLN02366; spermidine synthase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    148675970..148679076
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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