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S100a6 S100 calcium binding protein A6 (calcyclin) [ Mus musculus (house mouse) ]

Gene ID: 20200, updated on 23-Jun-2021

Summary

Official Symbol
S100a6provided by MGI
Official Full Name
S100 calcium binding protein A6 (calcyclin)provided by MGI
Primary source
MGI:MGI:1339467
See related
Ensembl:ENSMUSG00000001025
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2A; 2A9; Cac; PRA; 5B10; CALC; Cacy; CALCYCLIN
Expression
Biased expression in bladder adult (RPKM 1598.0), colon adult (RPKM 575.5) and 9 other tissues See more
Orthologs
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Genomic context

See S100a6 in Genome Data Viewer
Location:
3 F1; 3 39.35 cM
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (90520201..90521721)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (90612894..90614414)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (90416816..90418336)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene S100 calcium binding protein A4 Neighboring gene S100 calcium binding protein A5 Neighboring gene predicted gene, 19739 Neighboring gene S100 calcium binding protein A7A

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables S100 protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables S100 protein binding ISO
Inferred from Sequence Orthology
more info
 
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables calcium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables calcium ion binding ISO
Inferred from Sequence Orthology
more info
 
enables calcium-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables calcium-dependent protein binding ISO
Inferred from Sequence Orthology
more info
 
enables ion transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
enables tropomyosin binding ISO
Inferred from Sequence Orthology
more info
 
enables zinc ion binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix HDA PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in extrinsic component of cytoplasmic side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear envelope ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
is_active_in perinuclear region of cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in ruffle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein S100-A6
Names
S100 calcium-binding protein A6
calcium binding protein A6 (calcyclin)
prolactin receptor-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011313.2NP_035443.1  protein S100-A6

    See identical proteins and their annotated locations for NP_035443.1

    Status: VALIDATED

    Source sequence(s)
    AK008941, BM932500
    Consensus CDS
    CCDS38506.1
    UniProtKB/Swiss-Prot
    P14069
    UniProtKB/TrEMBL
    Q545I9
    Related
    ENSMUSP00000001051.5, ENSMUST00000001051.9
    Conserved Domains (1) summary
    cd05029
    Location:188
    S-100A6; S-100A6 domain found in proteins similar to S100A6. S100A6 is a member of the S100 domain family within EF-hand Ca2+-binding proteins superfamily. Note that the S-100 hierarchy, to which this S-100A6 group belongs, contains only S-100 EF-hand domains, ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    90520201..90521721
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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