Format

Send to:

Choose Destination

aco-2 putative aconitate hydratase, mitochondrial [ Caenorhabditis elegans ]

Gene ID: 176121, updated on 10-Aug-2021

Summary

Gene symbol
aco-2
Gene description
putative aconitate hydratase, mitochondrial
Primary source
WormBase:WBGene00000041
Locus tag
CELE_F54H12.1
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See aco-2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
6
Sequence:
Chromosome: III; NC_003281.10 (7973717..7977355)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene putative elongation factor 1-beta/1-delta 1 Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene tRNA Neighboring gene ncRNA Neighboring gene Calpain clp-1

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the aco-2 gene: The aco-2 gene is conserved in human, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, and frog.
  • Orthologs

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables aconitate hydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables aconitate hydratase activity IEA
Inferred from Electronic Annotation
more info
 
enables citrate dehydratase activity IEA
Inferred from Electronic Annotation
more info
 
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in tricarboxylic acid cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
putative aconitate hydratase, mitochondrial
NP_498738.2
  • Confirmed by transcript evidence
NP_741235.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    7973717..7977355
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171200.5NP_741235.1  putative aconitate hydratase, mitochondrial [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741235.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34455
    Conserved Domains (3) summary
    cd01584
    Location:92502
    AcnA_Mitochondrial; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle
    cd01578
    Location:581729
    AcnA_Mitochon_Swivel; Mitochondrial aconitase A swivel domain. Aconitase (also known as aconitate hydratase and citrate hydro-lyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes ...
    TIGR01340
    Location:42769
    aconitase_mito; aconitate hydratase, mitochondrial
  2. NM_066337.8NP_498738.2  putative aconitate hydratase, mitochondrial [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498738.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34455
    Conserved Domains (3) summary
    cd01584
    Location:1408
    AcnA_Mitochondrial; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle
    cd01578
    Location:487635
    AcnA_Mitochon_Swivel; Mitochondrial aconitase A swivel domain. Aconitase (also known as aconitate hydratase and citrate hydro-lyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes ...
    TIGR01340
    Location:1675
    aconitase_mito; aconitate hydratase, mitochondrial
Support Center