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Klrc1 killer cell lectin-like receptor subfamily C, member 1 [ Mus musculus (house mouse) ]

Gene ID: 16641, updated on 16-Oct-2021

Summary

Official Symbol
Klrc1provided by MGI
Official Full Name
killer cell lectin-like receptor subfamily C, member 1provided by MGI
Primary source
MGI:MGI:1336161
See related
Ensembl:ENSMUSG00000030167
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NKG2A; NKG2B; CD159a
Expression
Low expression observed in reference dataset See more
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Genomic context

See Klrc1 in Genome Data Viewer
Location:
6; 6 F3
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (129642978..129659815, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (129666015..129682852, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (129624877..129628928, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene killer cell lectin-like receptor subfamily C, member 3 Neighboring gene killer cell lectin-like receptor subfamily C, member 2 Neighboring gene microRNA 680-1 Neighboring gene PQ loop repeat containing pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

General protein information

Preferred Names
NKG2-A/NKG2-B type II integral membrane protein
Names
Cluster of Differentiation 159a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001136068.2NP_001129540.1  NKG2-A/NKG2-B type II integral membrane protein isoform 1

    See identical proteins and their annotated locations for NP_001129540.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC171002, AF106008
    Consensus CDS
    CCDS51926.1
    UniProtKB/TrEMBL
    Q9Z202
    Related
    ENSMUSP00000032270.7, ENSMUST00000032270.13
    Conserved Domains (1) summary
    cd03593
    Location:128240
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
  2. NM_001288664.1NP_001275593.1  NKG2-A/NKG2-B type II integral membrane protein isoform 3

    See identical proteins and their annotated locations for NP_001275593.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 3 which is shorter than isoform 1.
    Source sequence(s)
    AC171002, AF106008, AF106009
    Consensus CDS
    CCDS80621.1
    UniProtKB/TrEMBL
    E9QAJ6, Q9WVJ8, Q9Z202
    Related
    ENSMUSP00000130762.2, ENSMUST00000169545.8
    Conserved Domains (1) summary
    cd03593
    Location:94206
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
  3. NM_010652.2NP_034782.1  NKG2-A/NKG2-B type II integral membrane protein isoform 2

    See identical proteins and their annotated locations for NP_034782.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2 which is shorter than isoform 1.
    Source sequence(s)
    AC171002, AF106008, AF109784
    Consensus CDS
    CCDS39663.1
    UniProtKB/TrEMBL
    Q9WU32, Q9Z202
    Related
    ENSMUSP00000114017.2, ENSMUST00000118447.2
    Conserved Domains (1) summary
    cd03593
    Location:111223
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    129642978..129659815 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017321418.1XP_017176907.1  NKG2-A/NKG2-B type II integral membrane protein isoform X3

    UniProtKB/TrEMBL
    E9QAJ6
    Conserved Domains (1) summary
    cd03593
    Location:94206
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
  2. XM_011241237.1XP_011239539.1  NKG2-A/NKG2-B type II integral membrane protein isoform X2

    See identical proteins and their annotated locations for XP_011239539.1

    UniProtKB/TrEMBL
    Q9WU32
    Conserved Domains (1) summary
    cd03593
    Location:111223
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
  3. XM_011241236.1XP_011239538.1  NKG2-A/NKG2-B type II integral membrane protein isoform X1

    See identical proteins and their annotated locations for XP_011239538.1

    UniProtKB/TrEMBL
    Q9Z202
    Conserved Domains (1) summary
    cd03593
    Location:128240
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
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