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Icam5 intercellular adhesion molecule 5, telencephalin [ Mus musculus (house mouse) ]

Gene ID: 15898, updated on 17-Aug-2021

Summary

Official Symbol
Icam5provided by MGI
Official Full Name
intercellular adhesion molecule 5, telencephalinprovided by MGI
Primary source
MGI:MGI:109430
See related
Ensembl:ENSMUSG00000032174
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
T; Tl; Ica; TLN; CD50; Tlcn; Icam3; ICAM-3
Expression
Biased expression in frontal lobe adult (RPKM 62.6), cortex adult (RPKM 49.2) and 1 other tissue See more
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Genomic context

See Icam5 in Genome Data Viewer
Location:
9 A3; 9 7.7 cM
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (20943158..20950332)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (21032038..21039036)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (20836482..20843480)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene intercellular adhesion molecule 1 Neighboring gene intercellular adhesion molecule 4, Landsteiner-Wiener blood group Neighboring gene microRNA 1900 Neighboring gene zinc finger, GATA-like protein 1 Neighboring gene predicted gene, 38431 Neighboring gene ferredoxin 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC130520

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables integrin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within phagocytosis IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
intercellular adhesion molecule 5
Names
ICAM-5
intercellular adhesion molecule 3
telencephalin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008319.2NP_032345.2  intercellular adhesion molecule 5 precursor

    See identical proteins and their annotated locations for NP_032345.2

    Status: VALIDATED

    Source sequence(s)
    AC159314, AK135040, BB299138, BC113140, BY255874
    Consensus CDS
    CCDS22891.1
    UniProtKB/Swiss-Prot
    Q60625
    Related
    ENSMUSP00000019616.5, ENSMUST00000019616.6
    Conserved Domains (6) summary
    cd05755
    Location:120219
    Ig2_ICAM-1_like; Second immunoglobulin (Ig)-like domain of intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins
    smart00408
    Location:759819
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:756829
    IG_like; Immunoglobulin like
    pfam03921
    Location:32103
    ICAM_N; Intercellular adhesion molecule (ICAM), N-terminal domain
    pfam07679
    Location:572659
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:687742
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    20943158..20950332
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036154614.1XP_036010507.1  intercellular adhesion molecule 5 isoform X1

    Conserved Domains (3) summary
    smart00409
    Location:577650
    IG; Immunoglobulin
    cd00096
    Location:17
    Ig; Ig strand E [structural motif]
    cl11960
    Location:140
    Ig; Immunoglobulin domain
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