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Cstb cystatin B [ Mus musculus (house mouse) ]

Gene ID: 13014, updated on 18-Sep-2021

Summary

Official Symbol
Cstbprovided by MGI
Official Full Name
cystatin Bprovided by MGI
Primary source
MGI:MGI:109514
See related
Ensembl:ENSMUSG00000005054
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Stf; Stfb; AA960480
Expression
Broad expression in placenta adult (RPKM 262.8), bladder adult (RPKM 67.0) and 20 other tissues See more
Orthologs
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Genomic context

See Cstb in Genome Data Viewer
Location:
10 C1; 10 39.72 cM
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (78261504..78263456)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (78425670..78427622)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (77888415..77890367)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene LSM7 homolog, U6 small nuclear RNA associated pseudogene Neighboring gene ribosomal RNA processing 1 Neighboring gene microRNA 6907 Neighboring gene microRNA 6410 Neighboring gene pyridoxal (pyridoxine, vitamin B6) kinase Neighboring gene microRNA 6908

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cysteine-type endopeptidase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables cysteine-type endopeptidase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
enables endopeptidase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
enables peptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
enables protease binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within adult locomotory behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of peptidase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of proteolysis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix HDA PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007793.3NP_031819.1  cystatin-B

    See identical proteins and their annotated locations for NP_031819.1

    Status: VALIDATED

    Source sequence(s)
    BC056170, BY091749
    Consensus CDS
    CCDS23964.1
    UniProtKB/Swiss-Prot
    Q62426
    Related
    ENSMUSP00000005185.7, ENSMUST00000005185.8
    Conserved Domains (1) summary
    pfam00031
    Location:492
    Cystatin; Cystatin domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    78261504..78263456
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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