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Slc16a6 solute carrier family 16 (monocarboxylic acid transporters), member 6 [ Mus musculus (house mouse) ]

Gene ID: 104681, updated on 23-Jun-2021

Summary

Official Symbol
Slc16a6provided by MGI
Official Full Name
solute carrier family 16 (monocarboxylic acid transporters), member 6provided by MGI
Primary source
MGI:MGI:2144585
See related
Ensembl:ENSMUSG00000041920
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MCT6; MCT 6; MCT 7; ESTM12; AW743111
Expression
Ubiquitous expression in liver E14.5 (RPKM 4.3), liver E14 (RPKM 4.2) and 28 other tissues See more
Orthologs
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Genomic context

See Slc16a6 in Genome Data Viewer
Location:
11; 11 E1
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (109341681..109366428, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (109450855..109473598, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (109312169..109334910, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene 11696 Neighboring gene guanine nucleotide binding protein, alpha 13 Neighboring gene archaelysin family metallopeptidase 2 Neighboring gene predicted gene, 45916 Neighboring gene arylsulfatase G Neighboring gene predicted gene, 22378 Neighboring gene predicted gene, 39442 Neighboring gene WD repeat domain, phosphoinositide interacting 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (1) 

General gene information

Markers

Homology

Clone Names

  • MGC27628

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables monocarboxylic acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables symporter activity IEA
Inferred from Electronic Annotation
more info
 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in monocarboxylic acid transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
monocarboxylate transporter 7
Names
monocarboxylate transporter 6
solute carrier family 16 member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001029842.2NP_001025013.1  monocarboxylate transporter 7 isoform a

    See identical proteins and their annotated locations for NP_001025013.1

    Status: VALIDATED

    Source sequence(s)
    AK032026, AL645791, BC017129, CX238364
    Consensus CDS
    CCDS25580.1
    UniProtKB/Swiss-Prot
    B1AT66
    Related
    ENSMUSP00000065628.6, ENSMUST00000070152.12
    Conserved Domains (2) summary
    cd06174
    Location:109556
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00892
    Location:101592
    2A0113; monocarboxylate transporter 1
  2. NM_001363364.1NP_001350293.1  monocarboxylate transporter 7 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL645791
    Conserved Domains (1) summary
    cd17422
    Location:40488
    MFS_MCT7; Monocarboxylate transporter 7 of the Major Facilitator Superfamily of transporters
  3. NM_134038.3NP_598799.1  monocarboxylate transporter 7 isoform b

    See identical proteins and their annotated locations for NP_598799.1

    Status: VALIDATED

    Source sequence(s)
    AL645791, BC017129
    Consensus CDS
    CCDS36360.1
    UniProtKB/Swiss-Prot
    B1AT66
    Related
    ENSMUSP00000067423.7, ENSMUST00000070872.13
    Conserved Domains (1) summary
    cd17422
    Location:24472
    MFS_MCT7; Monocarboxylate transporter 7 of the Major Facilitator Superfamily of transporters

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    109341681..109366428 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156212.1XP_036012105.1  monocarboxylate transporter 7 isoform X4

    Conserved Domains (1) summary
    cl28910
    Location:108465
    MFS; Major Facilitator Superfamily
  2. XM_036156210.1XP_036012103.1  monocarboxylate transporter 7 isoform X1

    Conserved Domains (1) summary
    cd17422
    Location:108508
    MFS_MCT7; Monocarboxylate transporter 7 of the Major Facilitator Superfamily of transporters
  3. XM_017314216.3XP_017169705.1  monocarboxylate transporter 7 isoform X2

    Conserved Domains (1) summary
    cd17422
    Location:40488
    MFS_MCT7; Monocarboxylate transporter 7 of the Major Facilitator Superfamily of transporters
  4. XM_036156214.1XP_036012107.1  monocarboxylate transporter 7 isoform X5

    Conserved Domains (1) summary
    cd17422
    Location:24424
    MFS_MCT7; Monocarboxylate transporter 7 of the Major Facilitator Superfamily of transporters
  5. XM_036156211.1XP_036012104.1  monocarboxylate transporter 7 isoform X3

    Conserved Domains (1) summary
    cd17422
    Location:24472
    MFS_MCT7; Monocarboxylate transporter 7 of the Major Facilitator Superfamily of transporters
  6. XM_036156213.1XP_036012106.1  monocarboxylate transporter 7 isoform X5

    Conserved Domains (1) summary
    cd17422
    Location:24424
    MFS_MCT7; Monocarboxylate transporter 7 of the Major Facilitator Superfamily of transporters
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