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Tmprss2 transmembrane serine protease 2 [ Mesocricetus auratus (golden hamster) ]

Gene ID: 101843596, updated on 16-Apr-2021

Summary

Gene symbol
Tmprss2
Gene description
transmembrane serine protease 2
See related
Ensembl:ENSMAUG00000018948
Gene type
protein coding
RefSeq status
MODEL
Organism
Mesocricetus auratus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Mesocricetus
Orthologs
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Genomic context

See Tmprss2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
103 current BCM_Maur_2.0 (GCF_017639785.1) Unplaced Scaffold NW_024429192.1 (508992..546250)
102 previous assembly MesAur1.0 (GCF_000349665.1) Unplaced Scaffold NW_004801646.1 (529827..567120)

NW_024429192.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L7a-like Neighboring gene uncharacterized LOC121141739 Neighboring gene MX dynamin like GTPase 1 Neighboring gene FAM3 metabolism regulating signaling molecule B Neighboring gene beta-secretase 2

Genomic regions, transcripts, and products

General protein information

Preferred Names
transmembrane protease serine 2
Names
transmembrane protease, serine 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mesocricetus auratus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCM_Maur_2.0 Primary Assembly

Genomic

  1. NW_024429192.1 Reference BCM_Maur_2.0 Primary Assembly

    Range
    508992..546250
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013116227.3XP_012971681.1  transmembrane protease serine 2 isoform X1

    UniProtKB/TrEMBL
    A0A1U8BWQ2
    Conserved Domains (4) summary
    smart00020
    Location:274503
    Tryp_SPc; Trypsin-like serine protease
    cd00112
    Location:113148
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:275506
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:173268
    SRCR_2; Scavenger receptor cysteine-rich domain
  2. XM_013116228.3XP_012971682.1  transmembrane protease serine 2 isoform X2

    UniProtKB/TrEMBL
    A0A1U8BWQ1
    Conserved Domains (4) summary
    smart00020
    Location:273502
    Tryp_SPc; Trypsin-like serine protease
    cd00112
    Location:113148
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:274505
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:172267
    SRCR_2; Scavenger receptor cysteine-rich domain
  3. XM_013116229.3XP_012971683.1  transmembrane protease serine 2 isoform X3

    UniProtKB/TrEMBL
    A0A1U8C7C8
    Conserved Domains (4) summary
    smart00020
    Location:255484
    Tryp_SPc; Trypsin-like serine protease
    cd00112
    Location:113148
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:256487
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:154249
    SRCR_2; Scavenger receptor cysteine-rich domain
  4. XM_013116230.3XP_012971684.1  transmembrane protease serine 2 isoform X4

    UniProtKB/TrEMBL
    A0A1U8C7X1
    Related
    ENSMAUP00000021134.1
    Conserved Domains (4) summary
    smart00020
    Location:254483
    Tryp_SPc; Trypsin-like serine protease
    cd00112
    Location:113148
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:255486
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:153248
    SRCR_2; Scavenger receptor cysteine-rich domain
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