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Tmprss2 transmembrane serine protease 2 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101715175, updated on 6-Jul-2020

Summary

Gene symbol
Tmprss2
Gene description
transmembrane serine protease 2
Locus tag
GW7_10196
See related
Ensembl:ENSHGLG00000018181
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
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Genomic context

See Tmprss2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
16
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624745.1 (28565515..28593102)

NW_004624745.1Genomic Context describing neighboring genes Neighboring gene receptor interacting serine/threonine kinase 4 Neighboring gene uncharacterized LOC110348678 Neighboring gene uncharacterized LOC110348677 Neighboring gene interferon-induced GTP-binding protein Mx2 Neighboring gene uncharacterized LOC101716457

Genomic regions, transcripts, and products

Genomic Sequence:
NW_004624745 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

General protein information

Preferred Names
transmembrane protease serine 2
Names
transmembrane protease, serine 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624745.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    28565515..28593102
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021256350.1XP_021112009.1  transmembrane protease serine 2 isoform X3

    Conserved Domains (3) summary
    smart00020
    Location:253450
    Tryp_SPc; Trypsin-like serine protease
    cd00112
    Location:112147
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam15494
    Location:152247
    SRCR_2; Scavenger receptor cysteine-rich domain
  2. XM_004842461.3XP_004842518.1  transmembrane protease serine 2 isoform X2

    Conserved Domains (4) summary
    smart00020
    Location:246475
    Tryp_SPc; Trypsin-like serine protease
    cd00112
    Location:112147
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:247478
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:152241
    SRCR_2; Scavenger receptor cysteine-rich domain
  3. XM_004842457.3XP_004842514.1  transmembrane protease serine 2 isoform X1

    See identical proteins and their annotated locations for XP_004842514.1

    Related
    ENSHGLP00000025524.1, ENSHGLT00000025750.1
    Conserved Domains (4) summary
    smart00020
    Location:253482
    Tryp_SPc; Trypsin-like serine protease
    cd00112
    Location:112147
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:254485
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:152247
    SRCR_2; Scavenger receptor cysteine-rich domain
  4. XM_004842459.3XP_004842516.1  transmembrane protease serine 2 isoform X1

    See identical proteins and their annotated locations for XP_004842516.1

    Conserved Domains (4) summary
    smart00020
    Location:253482
    Tryp_SPc; Trypsin-like serine protease
    cd00112
    Location:112147
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:254485
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:152247
    SRCR_2; Scavenger receptor cysteine-rich domain
  5. XM_004842460.3XP_004842517.1  transmembrane protease serine 2 isoform X1

    See identical proteins and their annotated locations for XP_004842517.1

    Conserved Domains (4) summary
    smart00020
    Location:253482
    Tryp_SPc; Trypsin-like serine protease
    cd00112
    Location:112147
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:254485
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:152247
    SRCR_2; Scavenger receptor cysteine-rich domain
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