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Psph phosphoserine phosphatase [ Mus musculus (house mouse) ]

Gene ID: 100678, updated on 6-May-2021

Summary

Official Symbol
Psphprovided by MGI
Official Full Name
phosphoserine phosphataseprovided by MGI
Primary source
MGI:MGI:97788
See related
Ensembl:ENSMUSG00000029446
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
P; PSP; PSPase; AI480570
Expression
Ubiquitous expression in placenta adult (RPKM 14.8), liver E14 (RPKM 8.2) and 28 other tissues See more
Orthologs
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Genomic context

See Psph in Genome Data Viewer
Location:
5; 5 G1.3
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (129842622..129864318, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (129765558..129787443, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (130271434..130293129, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein S17 Neighboring gene nipsnap homolog 2 Neighboring gene predicted gene, 23245 Neighboring gene chaperonin containing Tcp1, subunit 6a (zeta) Neighboring gene small nucleolar RNA, H/ACA box 15

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (3) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables L-phosphoserine phosphatase activity ISO
Inferred from Sequence Orthology
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables magnesium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables magnesium ion binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphoserine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables phosphoserine phosphatase activity ISO
Inferred from Sequence Orthology
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in L-serine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in L-serine biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in L-serine metabolic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within cellular amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within in utero embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in neuron projection ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
phosphoserine phosphatase
Names
O-phosphoserine phosphohydrolase
NP_598661.1
XP_006504337.1
XP_006504338.1
XP_017176063.1
XP_030109871.1
XP_030109872.1
XP_030109873.1
XP_036020582.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133900.4NP_598661.1  phosphoserine phosphatase

    See identical proteins and their annotated locations for NP_598661.1

    Status: VALIDATED

    Source sequence(s)
    AA003039, AI841354, BQ177662, BY125431, BY127546, CV560928
    Consensus CDS
    CCDS19699.1
    UniProtKB/Swiss-Prot
    Q99LS3
    Related
    ENSMUSP00000031399.7, ENSMUST00000031399.13
    Conserved Domains (1) summary
    cd04309
    Location:15216
    HAD_PSP_eu; phosphoserine phosphatase eukaryotic-like, similar to human phosphoserine phosphatase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    129842622..129864318 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006504274.5XP_006504337.1  phosphoserine phosphatase isoform X1

    See identical proteins and their annotated locations for XP_006504337.1

    UniProtKB/Swiss-Prot
    Q99LS3
    Conserved Domains (1) summary
    cd04309
    Location:15216
    HAD_PSP_eu; phosphoserine phosphatase eukaryotic-like, similar to human phosphoserine phosphatase
  2. XM_030254011.1XP_030109871.1  phosphoserine phosphatase isoform X1

    Conserved Domains (1) summary
    cd04309
    Location:15216
    HAD_PSP_eu; phosphoserine phosphatase eukaryotic-like, similar to human phosphoserine phosphatase
  3. XM_036164689.1XP_036020582.1  phosphoserine phosphatase isoform X1

    Conserved Domains (1) summary
    cd04309
    Location:15216
    HAD_PSP_eu; phosphoserine phosphatase eukaryotic-like, similar to human phosphoserine phosphatase
  4. XM_030254012.2XP_030109872.1  phosphoserine phosphatase isoform X1

    Conserved Domains (1) summary
    cd04309
    Location:15216
    HAD_PSP_eu; phosphoserine phosphatase eukaryotic-like, similar to human phosphoserine phosphatase
  5. XM_030254013.2XP_030109873.1  phosphoserine phosphatase isoform X1

    Conserved Domains (1) summary
    cd04309
    Location:15216
    HAD_PSP_eu; phosphoserine phosphatase eukaryotic-like, similar to human phosphoserine phosphatase
  6. XM_017320574.1XP_017176063.1  phosphoserine phosphatase isoform X1

    UniProtKB/Swiss-Prot
    Q99LS3
    Conserved Domains (1) summary
    cd04309
    Location:15216
    HAD_PSP_eu; phosphoserine phosphatase eukaryotic-like, similar to human phosphoserine phosphatase
  7. XM_006504275.4XP_006504338.1  phosphoserine phosphatase isoform X2

    Conserved Domains (1) summary
    cd04309
    Location:1165
    HAD_PSP_eu; phosphoserine phosphatase eukaryotic-like, similar to human phosphoserine phosphatase
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