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Items: 1 to 20 of 23117

1.

Revealing pathways associated with feed efficiency and meat quality traits in slow-growing chicken

(Submitter supplied) Improvement of feed efficiency would increase profitability of the poultry industries by decreasing the amount of feed required for production. Korat (KR) chicken is a new alternative meat-type chicken breed which its meat is recognized for its high protein, low fat and low purine content, whereas its low feed efficiency leads to high cost of production. Deeper understanding on how feed efficiency influences meat quality is poorly elucidated. more...
Organism:
Gallus gallus
Type:
Expression profiling by array
Platform:
GPL20588
24 Samples
Download data: TXT
Series
Accession:
GSE162848
ID:
200162848
2.

How experimental competition changes ovarian gene activity in free living birds: implications for steroidogenesis, maternal effects, and beyond

(Submitter supplied) The ovary plays an important role in mediating both a female’s response to her own social environment and communicating it to her developing offspring. However, we know little about the underlying genomic mechanisms that facilitate social responsiveness in the ovary. This issue is further complicated by mixed support linking female competition to ovarian production of testosterone, the often-evoked mechanism mediating both social aggression and maternal effects. more...
Organism:
Tachycineta bicolor
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26161
20 Samples
Download data: TSV
Series
Accession:
GSE184993
ID:
200184993
3.

Jejunal Transcriptomic Profiling for Differences in Feed Conversion Ratio in Slow-Growing Chickens

(Submitter supplied) Slow-growing Korat chicken (KR) is an alternative to broiler chickens that has been used as a national tool to support smallholder farmers due to a higher selling price of KR meat. However, the individual variability of feed efficiency (FE) within a KR stockbreeding results in a lack of competitiveness. Therefore, improvement of FE of KR is of major importance to improve the profitability of livestock production enterprises. more...
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24517
6 Samples
Download data: XLSX
Series
Accession:
GSE178916
ID:
200178916
4.

Ad Libitum Feeding in Broiler Breeder Hens Alters Transcriptome of Granulosa Cells of Prehierarchal Follicles

(Submitter supplied) Intense selective breeding of broiler breeds of chickens has resulted in suboptimal egg production in broiler breeder hens. Ad libitum feeding which leads to excessive and disorganized follicular growth exacerbates this reproductive phenotype. One strategy used to improve broiler breeder hen reproductive efficiency is restricted feeding. In this study, we sought to identify transcriptional changes which translate level of dietary intake to increased follicle selection. more...
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL27748
5 Samples
Download data: XLSX
Series
Accession:
GSE175887
ID:
200175887
5.

Dual RNA-seq transcriptome analysis of chicken caeca infected with Eimeria tenella

(Submitter supplied) In order to elucidate the infection mechanisms of Eimeria tenella and the chicken immune response, chickens were infected with Eimeria tenella strain Hougton sporozoites. Samples were taken at 0, 1, 2, 3, 4 and 10 days post-infection and mRNA sequenced. A dual-RNA seq analysis was carried out, comparing the expression of infected chickens during each sampling time point with uninfected chickens and comparing E. more...
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26853
36 Samples
Download data: CSV
Series
Accession:
GSE160169
ID:
200160169
6.

Characterization of duck peripheral blood cells at single-cell resolution

(Submitter supplied) We performed scRNA-seq for duck peripheral white blood cells.
Organism:
Anas platyrhynchos
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL29169 GPL22591
13 Samples
Download data: MTX, TSV, TXT
Series
Accession:
GSE153825
ID:
200153825
7.

Expression data from ad libitum or restricted fed 16-week old broiler breeder hens

(Submitter supplied) Ovarian dysfunction is observed in broiler breeder hens fed ad libitum that is most apparent by a reduction in fertility success. Restricting caloric intake in these hens is currently the only effective treatment to improve reproductive efficiency. This analysis sought to determine the transcriptional changes in the ovarian cortex of prepubertal hens given full access to feed (FF) or were placed on a restricted feed (RF) diet. more...
Organism:
Gallus gallus
Type:
Expression profiling by array
Platform:
GPL3213
6 Samples
Download data: CEL
Series
Accession:
GSE184105
ID:
200184105
8.

Transcriptome analysis reveals the roles of long non-coding RNA and mRNA in bursa of Fabricius during pigeon (Columba livia) development

(Submitter supplied) We identified 13,072 mRNAs and 19,129 lncRNAs, of which 2,977 mRNAs and 1,527 lncRNAs were differential expressed in pigeon BFs over three developmental stages.
Organism:
Columba livia
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platform:
GPL29485
9 Samples
Download data: TXT
Series
Accession:
GSE183791
ID:
200183791
9.

Single cell atlas for mammals, reptiles and birds

(Submitter supplied) The availability of viral entry factors is a prerequisite for the cross-species transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Large-scale single-cell screening on animal cells is a powerful tool to reveal the expression patterns of viral entry genes for different hosts. But such exploration for SARS-CoV-2 remained limited. Here, we presented the broadest pan-species single-nucleus RNA sequencing study to date, covering 11 representative species in pets (cat, dog, hamster, lizard), livestock (goat, rabbit), poultry (duck, pigeon) and wildlife (pangolin, tiger, deer), from which we investigated the co-expression of ACE2 and TMPRSS2. more...
Organism:
Anas platyrhynchos; Canis lupus familiaris; Anolis carolinensis; Panthera tigris altaica; Oryctolagus cuniculus; Mesocricetus auratus; Columba livia; Felis catus; Capra aegagrus; Manis javanica; Cervus nippon taiouanus
Type:
Expression profiling by high throughput sequencing
11 related Platforms
29 Samples
Download data: TXT
Series
Accession:
GSE183300
ID:
200183300
10.

RNA Profiles of the Korat Chicken Breast Muscle with Increased Carnosine Content Produced through Dietary Supplementation with β-Alanine or L-Histidine

(Submitter supplied) Carnosine is a bioactive food component with several potential health benefits for humans due to its physiological functions. Dietary supplementation with β-alanine or L-histidine can increase the carnosine content of skeletal muscles in chickens. Dietary supplementation with β-alanine or L-histidine has produced a slow-growing chicken variety with high carnosine content in the breast meat; however, the supplementation with L-histidine alone softens the meat toughness, which may affect consumers’ willingness to buy the meat. more...
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26853
15 Samples
Download data: XLSX
Series
Accession:
GSE179643
ID:
200179643
11.

Applying of transcriptomics to screen the significantly altered genes, cell function and signal transduction pathway of chicken trachea exposed to hydrogen sulfide

(Submitter supplied) Hydrogen sulfide (H2S) is well known to cause irritation and damage to airway following inhalation, but the mechanism by which H2S contributes to airway toxicity is unclear. We apply transcriptomics to demonstrate the possible effects, obtain valuable information about adverse health effects following H2S exposure and to study the molecular mechanisms of the gas toxicity in trachea.
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24517
4 Samples
Download data: TXT
Series
Accession:
GSE119429
ID:
200119429
12.

Position Specific Alternative Splicing and Gene Expression Profiles along the Tonotopic Axis of Chick Cochlea

(Submitter supplied) We performed an RNA-Seq experiment for three sample groups on base, middle, and apex regions of chick cochlea to identify genes and splicing events whose regulation mechanisms are associated with tonotopy.
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL23499
9 Samples
Download data: TXT
Series
Accession:
GSE176521
ID:
200176521
13.

Distruption of DMRT1 induces feminization in Chicken

(Submitter supplied) RNA-sequencing data to inversigate the effects of DMRT1-distruption at E6 and 1W time points in male and female chickens.
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24996
24 Samples
Download data: TXT
Series
Accession:
GSE150339
ID:
200150339
14.

Next Generation Sequencing of ileum in broiler infected with S. pullorum

(Submitter supplied) This study was conducted to evaluate the effects of dietary supplemental magnolol and honokiol in broilers infected with S. pullorum. A total of 360 one-day-old broilers were selected and randomly divided into four groups with six replicates: the negative control group (CTL), S. pullorum-infected group (SP), and the S. pullorum-infected group supplemented with 300 mg/kg honokiol (SPH) or magnolol (SPM). more...
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26853
24 Samples
Download data: TXT
Series
Accession:
GSE164260
ID:
200164260
15.

Metformin affects transcriptomic pathways involved in cell survival, metabolism and angiogenesis in ovarian cancer cells

(Submitter supplied) The objectives of the present study are to determine the effect of metformin on sphere formation, extracellular matrix invasion, and transcriptome profile of ovarian cancer (COVCAR) cells isolated from ascites of chickens that naturally developed ovarian cancer. Our results suggest that metformin treatment significantly decreased sphere formation and invasiveness of COVCAR cells. Pairwise statistical analysis of transcriptomic data using Deseq2 software revealed 0, 4, 365 genes that were differentially expressed (DEGs) in cells treated with 0.5, 1, 2 mM metformin-treated cells compared to controls, respectively.
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19005
16 Samples
Download data: CSV
Series
Accession:
GSE182084
ID:
200182084
16.

HOXB8 counteracts MAPK/ERK oncogenic signaling in a chicken embryo model of neoplasia

(Submitter supplied) HOX transcription factors are members of an evolutionarily conserved family of proteins required for the establishment of the anteroposterior body axis during bilaterian development. Although they are often deregulated in cancers, the molecular mechanisms by which they act as oncogenes or tumor suppressor genes are only partially understood. Since the MAPK/ERK signaling pathway is deregulated in most cancers, we aimed at apprehending if and how Hox proteins interact with ERK oncogenicity. more...
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16133
6 Samples
Download data: XLSX
Series
Accession:
GSE182076
ID:
200182076
17.

Sustained experimental activation of FGF8/ERK in the developing chicken spinal cord reproducibly models early events in ERK-mediated tumorigenesis

(Submitter supplied) Most human cancers demonstrate activated MAPK/ERK pathway signaling as a key tumor initiation step, but the immediate steps of further oncogenic progression are poorly understood due to a lack of appropriate models. Spinal cord differentiation follows caudal elongation in vertebrate embryos; both processes are regulated by a FGF8 gradient highest in neuromesodermal progenitors (NMP), where kinase effectors ERK1/2 maintain an undifferentiated state. more...
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16133
4 Samples
Download data: XLSX
Series
Accession:
GSE182072
ID:
200182072
18.

Comparative analysis among different species reveals that androgen receptor is a core transcriptional factor regulating the chicken follicular selection and ovulation [RNA-Seq 2]

(Submitter supplied) The differences in reproductive processes at the molecular level between viviparous and oviparous animals are evident, and the site in the ovary that synthesizes sex hormones (androgens and oestrogens) and the trends for enriching sex hormones during follicle development in chickens are different from those in mammals, suggesting that the effect of sex hormones on follicle development in chickens is probably different from that in viviparous animals. more...
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26853
6 Samples
Download data: CSV, GTF
Series
Accession:
GSE182083
ID:
200182083
19.

Regional specific differentiation of integumentary organs: SATB2 is involved in α- and β-keratin gene cluster switching in the chicken

(Submitter supplied) Animals develop skin regional specificities to best adapt to their environments. Birds are excellent models in which to study the epigenetic mechanisms that facilitate these adaptions. Patients suffering from SATB2 mutations exhibit multiple defects including ectodermal dysplasia-like changes. The preferential expression of SATB2, a chromatin regulator, in feather-forming compared to scale-forming regions, suggests it functions in regional specification of chicken skin appendages by acting on either differentiation or morphogenesis. more...
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL16133 GPL19787
16 Samples
Download data: TXT
Series
Accession:
GSE178651
ID:
200178651
20.

Somatic piRNAs in veterbrate kidney

(Submitter supplied) SmallRNA seq and longRNA seq of chicken kidney and testis
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platform:
GPL16133
20 Samples
Download data: BED2, SF
Series
Accession:
GSE181811
ID:
200181811
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