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Links from Protein

Items: 1 to 20 of 145

1.

Cell adhesion molecules (CAMs)

Cell adhesion molecules are (glyco)proteins expressed on the cell surface and play a critical role in a wide array of biologic processes that include hemostasis, the immune response, inflammation, embryogenesis, and development of neuronal tissue. There are four main groups: the integrin...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
2.

Neurofascin interactions

Neurofascin is an L1 family immunoglobulin cell adhesion molecule involved in axon subcellular targeting and synapse formation during neural development. There are a range of different isoforms identified in Neurofascin of which two of them are well studied the 186kDa commonly referred...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
3.

NOTCH2 Activation and Transmission of Signal to the Nucleus

Similar to NOTCH1, NOTCH2 is activated by Delta-like and Jagged ligands (DLL/JAG) expressed in trans on a neighboring cell (Shimizu et al. 1999, Shimizu et al. 2000, Hicks et al. 2000, Ji et al. 2004). The activation triggers cleavage of NOTCH2, first by ADAM10 at the S2 cleavage...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
4.

Activated NOTCH1 Transmits Signal to the Nucleus

Mature NOTCH1 heterodimer on the cell surface is activated by one of its ligands: DLL1 (Cordle et al. 2008, Jarriault et al. 1998), DLL4 (Benedito et al. 2009), JAG1 (Li et al. 1998, Benedito et al. 2009) or JAG2 (Luo et al. 1997, Shimizu et al. 2000), expressed in trans on a neighboring...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
5.

L1CAM interactions

The L1 family of cell adhesion molecules (L1CAMs) are a subfamily of the immunoglobulin superfamily of transmembrane receptors, comprised of four structurally related proteins: L1, Close Homolog of L1 (CHL1), NrCAM, and Neurofascin. These CAMs contain six Ig like domains, five or...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
6.

Signaling by NOTCH2

NOTCH2 is activated by binding Delta-like and Jagged ligands (DLL/JAG) expressed in trans on neighboring cells (Shimizu et al. 1999, Shimizu et al. 2000, Hicks et al. 2000, Ji et al. 2004). In trans ligand-receptor binding is followed by ADAM10 mediated (Gibb et al. 2010, Shimizu...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
7.

Signaling by NOTCH1

NOTCH1 functions as both a transmembrane receptor presented on the cell surface and as a transcriptional regulator in the nucleus.NOTCH1 receptor presented on the plasma membrane is activated by a membrane bound ligand expressed in trans on the surface of a neighboring cell. In trans,...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
8.

Notch signaling pathway

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
9.

Cell adhesion molecules (CAMs)

Cell adhesion molecules are (glyco)proteins expressed on the cell surface and play a critical role in a wide array of biologic processes that include hemostasis, the immune response, inflammation, embryogenesis, and development of neuronal tissue. There are four main groups: the integrin...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
10.

Developmental Biology

As a first step towards capturing the array of processes by which a fertilized egg gives rise to the diverse tissues of the body, examples of three kinds of processes have been annotated. These are aspects of the roles of cell adhesion molecules in axonal guidance and myogenesis,...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
11.

Signaling by NOTCH

The Notch Signaling Pathway (NSP) is a highly conserved pathway for cell-cell communication. NSP is involved in the regulation of cellular differentiation, proliferation, and specification. For example, it is utilised by continually renewing adult tissues such as blood, skin, and...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
12.

Signal Transduction

Signal transduction is a process in which extracellular signals elicit changes in cell state and activity. Transmembrane receptors sense changes in the cellular environment by binding ligands, such as hormones and growth factors, or reacting to other types of stimuli, such as light....

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
13.

extracellular vesicle

Any vesicle that is part of the extracellular region. Synonym: microparticle;

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1129387
GO
: GO:1903561
14.

carbohydrate derivative binding

Interacting selectively and non-covalently with a carbohydrate derivative.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
752867
GO
: GO:0097367
15.

single-organism developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, involving only one organism.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
751909
GO
: GO:0044767
16.

regulation of multicellular organismal development

Any process that modulates the frequency, rate or extent of multicellular organismal development.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
518675
GO
: GO:2000026
17.

cell periphery

The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
516864
GO
: GO:0071944
18.

extracellular exosome

A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. Synonyms: exosome; extracellular vesicular...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
515001
GO
: GO:0070062
19.

biological regulation

Any process that modulates a measurable attribute of any biological process, quality or function. Synonym: regulation;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
514938
GO
: GO:0065007
20.

head development

The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
513878
GO
: GO:0060322

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