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Links from BioSystems

Items: 1 to 20 of 62

1.

Oxidative phosphorylation

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
2.

Parkinson's disease

Parkinson's disease (PD) is a progressive neurodegenerative movement disorder that results primarily from the death of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc). Mutations in alpha-synuclein, UCHL1 (a ubiquitin carboxy-terminal hydrolase L1), parkin, DJ1...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
3.

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
4.

The citric acid (TCA) cycle and respiratory electron transport

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
5.

Respiratory electron transport

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
6.

V-type ATPase, eukaryotes

Structural complex; Energy metabolism; ATP synthesis

Type
:
structural_complex
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
BSID:
421810
KEGG
: mmu_M00160
7.

Insulin receptor recycling

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
8.

Transferrin endocytosis and recycling

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
9.

Huntington's disease

Huntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). The symptoms are choreiform, involuntary movements, personality changes and dementia. HD is caused by a CAG repeat expansion in the IT15gene, which...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
10.

Alzheimer's disease

Alzheimer's disease (AD) is a chronic disorder that slowly destroys neurons and causes serious cognitive disability. AD is associated with senile plaques and neurofibrillary tangles (NFTs). Amyloid-beta (Abeta), a major component of senile plaques, has various pathological effects...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
11.

Non-alcoholic fatty liver disease (NAFLD)

Non-alcoholic fatty liver disease (NAFLD) represents a spectrum ranging from simple steatosis to more severe steatohepatitis with hepatic inflammation and fibrosis, known as nonalcoholic steatohepatitis (NASH). NASH may further lead to cirrhosis and hepatocellular carcinoma (HCC)....

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
12.

Collecting duct acid secretion

One of the important roles of the collecting duct segment of the kidney nephron is acid secretion. As daily food intake loads acid into the body, urinary acid excretion is essential, and urine pH can drop as low as 4.5. The alpha-intercalated cell of collecting duct is the main responsible...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
13.

Iron uptake and transport

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
14.

Complex I biogenesis

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
15.

ROS, RNS production in phagocytes

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
16.

Synaptic vesicle cycle

Communication between neurons is mediated by the release of neurotransmitter from synaptic vesicles (SVs). At the nerve terminal, SVs cycle through repetitive episodes of exocytosis and endocytosis. SVs are filled with neurotransmitters by active transport. The loaded SVs are then...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
17.

Formation of ATP by chemiosmotic coupling

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
18.

F-type ATPase, eukaryotes

Structural complex; Energy metabolism; ATP synthesis

Type
:
structural_complex
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
BSID:
522571
KEGG
: mmu_M00158
19.

Cytochrome c oxidase

Structural complex; Energy metabolism; ATP synthesis

Type
:
structural_complex
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
BSID:
421838
KEGG
: mmu_M00154
20.

Rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic autoimmune joint disease where persistent inflammation affects bone remodeling leading to progressive bone destruction. In RA, abnormal activation of the immune system elevates pro-inflammatory cytokines and chemokines levels, which can promote...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus

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