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Transferrin endocytosis and recycling

Endocytosis of iron loaded transferrin/receptor complex leads, after acidification of the endosome, to the separation of iron and its diffusion out of the vesicle. The endosome is not fused with a lysosome but recycles its content back to the cell surface where soon transferrin dissociates from its receptor (Dautry-Varsat, 1986).

from REACTOME source record: R-HSA-917977
Type: pathway
Taxonomic scope
organism-specific biosystem
Homo sapiens

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