Conserved Protein Domain Family
YgiQ

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COG1032: YgiQ 
Radical SAM superfamily enzyme YgiQ, UPF0313 family [General function prediction only]
Statistics
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PSSM-Id: 223963
Aligned: 87 rows
Threshold Bit Score: 110.8
Threshold Setting Gi: 16082367
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
15641715  44 IVTGDAYVDHPSFGMAIIGRLLEAQGfrVGIIAQPEWQTKDAFMTLGKPN--LFFGVTAGNMDSMINRYTADKKIRHDDA 121 Vibrio cholerae
15673150  18 YLSLPVLKAYLQQNNQEVLIRDENVEfyDFFFSEQFFKRMSRETSTLKKSiyFNSTLHIQEAKDVIRSKDSKSWQRKFAW 97  Lactococcus lactis ...
18312415  12 APSVYDFRNLRRVHYGPISDVIPSRPv-FDMYPVGFIYIVSYLEKRGVKTg-IFNVAARMLNEPRLDVSKLLKGIKATLY 89  Pyrobaculum aerophilum
15607354   1 ---------------MSIKAYAK-------TQGIAVTSVNG--LVAGHGS-------VQETWLAMQSAAALSGTPR--LV 47  Mycobacterium tuber...
13542209  15 DFRKRDIDPGPISDVVPSTPVFEM-------YPVGFISMLNFLVQNGFNAr-IANVAVRMVESKKFNVEKYLSEIEAPIF 86  Thermoplasma volcanium
16081365   1 ---------------MPSTPVFEM-------YPVGFVSMLNYLVQNGFNAr-IANVAVRMVQSKRFDPISYLKDLEAPIY 57  Thermoplasma acidop...
16082367   1 MHEAIEFYHRQFPGVPIYVGGIYAS-----LMPEHIRASFPFVKMHVG-----FYPEAENLISAYHLLQQVEKWRSWDRS 70  Thermoplasma acidop...
17229515  32 KLEPTILYPNIQFAEEIGLDVYAMISenFIETFLGEWTFSGVLFPEFNPNhsEYFDLISPCFKSYENYLPDRNLKEAFLA 111 Nostoc sp. PCC 7120
13474043   1 -----MKIVLINPPHTAIGSRVPDDH----LPPLGLLAIGGPLIDAGHDVr-LVDAEFGPMPLDIVVRDALDDFPDFVLI 70  Mesorhizobium loti
16331659   1 -----MRILILNPPHPAIGSRIPKEQ----LPPLGLLSIGGPLLDAGHDVt-LLDAEFGPLTDSEIVERVCAHCPQLLLI 70  Synechocystis sp. P...
15641715 122 YTPNNKGGMRPDRCSLVYSQRCRE--AYKd---vPIVLGGIEASLRRVAHYDYWSdkvrrs------illdakADILLFG 190 Vibrio cholerae
15673150  98 NVLSNLNYLAGKVYKGFEIDFNSM--HFKyshdsTSEIMKALSDRAANPLIEYFEkdcsti-------eeiknQEIEYIG 168 Lactococcus lactis ...
18312415  90 AVDIHWLVHAHGAVEVAKLVKEIH--GAP------VAVGGFSATYYWREILEKYPf-----------------IDFVVLG 144 Pyrobaculum aerophilum
15607354  48 GFS-CID-TFPEVLWLAQRARQAW--DGV-----RIVIGNAMATLNYERILRQHDc-----------------FDYVVVG 101 Mycobacterium tuber...
13542209  87 GIDLHWLPHAHGALNLARIIKNIH--PES-----YVVFGGYSSTYFRYELMKNYDf-----------------IDFVLAG 142 Thermoplasma volcanium
16081365  58 GIDLHWLPHTHGALNLARIVKNLH--PNS-----YVVLGGYSSTYFRKEIMRDYPf-----------------IDFILAG 113 Thermoplasma acidop...
16082367  71 IVFTSRGCIRKCPFCVVPKVEGGMrdQKP------SIIDLMHPSHRKVTIWDN---------------------NFLASP 123 Thermoplasma acidop...
17229515 112 VREQATAFIESVAQSVANLQPRIIgcSSTfqqhcASLALLKRVRELAPEIITFMGgancegamglaththfswVDFIISG 191 Nostoc sp. PCC 7120
13474043  71 GHSGSTS-AHPTALLIAEMIKQRE--PAT-----IIIYGGVFPTYHWRDILTDTDv-----------------FDFIVRG 125 Mesorhizobium loti
16331659  71 GHSGSTS-AHPIVCRLTLFLRERL--PNL-----IIVYGGVFPTYHFHDILTKEPq-----------------IDFIVRG 125 Synechocystis sp. P...
15641715 191 NAERALVEVAHRLANGESInkmvdirgtavnlaqvpehfkiidstridqpnkpfvpsnpyevetqcatkgdekeeaqpit 270 Vibrio cholerae
15673150 169 FSVTGNTQLIPTLTMCKAIkelcpsvkhiqlg--------------------------------------gnfitrissl 210 Lactococcus lactis ...
18312415 145 DTTEPVIYQLLHAVERGDR------------------------------------------------------------- 163 Pyrobaculum aerophilum
15607354 102 DGEVAFTKLALALANDAAV------------------------------------------------------------- 120 Mycobacterium tuber...
13542209 143 DFQEYGIYKLAEALEEGASy------------------------------------------------------------ 162 Thermoplasma volcanium
16081365 114 DFQEYGIYKLAESIVEGRPl------------------------------------------------------------ 133 Thermoplasma acidop...
16082367 124 YAKSMLRELIDHGIEADFN------------------------------------------------------------- 142 Thermoplasma acidop...
17229515 192 EGDDLFNEFCYQLLDGGREvd----------------------------------------------------------- 212 Nostoc sp. PCC 7120
13474043 126 EGEATVVALVEALEMHQPP------------------------------------------------------------- 144 Mesorhizobium loti
16331659 126 EGEATVAKLIAALENHNDL------------------------------------------------------------- 144 Synechocystis sp. P...
15641715 271 irpSRhd-akTTAVRLPSFEKLVNDrilyahasrvLHLETNPYSGRALVQRHgdrelwvnqapipltteemdfvfglyyA 349 Vibrio cholerae
15673150 211 ignLHpfwnyIDSMLLYDGEENLSSflq----qleNNKDYSNIPNLYYLDDHrnlkrn---------------eiveskT 271 Lactococcus lactis ...
18312415 164 ---GKly--eIPNLAFRDGDKLVNTgiryipqeldDLKPDYTAVARAMIRSG---------------------------I 211 Pyrobaculum aerophilum
15607354 121 ---DD-----VPGLARRSEQGQIL-----------RTPSS--LVDLDELPRp---------------------------A 152 Mycobacterium tuber...
13542209 163 ---SE-----VPGLVYRENGRIKEN----------QRYDFRKGLDNVFLNYEvllkna----------------ikyhdV 208 Thermoplasma volcanium
16081365 134 ---SE-----VPGLVHRENGMIKEE----------RPYDFRKGLENVFFNYEvllkna----------------lkyhdV 179 Thermoplasma acidop...
16082367 143 -----------QGLDARLIDEETAG-----------LLADVKSKSIHMAY------------------------------ 170 Thermoplasma acidop...
17229515 213 -psILpygviSPSHRTSTKISIAAPra------svQNLDQVPIPDYDDYFQTl--------------------------H 259 Nostoc sp. PCC 7120
13474043 145 ---AS-----VAGIAFRDDLHRPF-----------ATQAAMTIAELDAYRVGw-------------------------eL 180 Mesorhizobium loti
16331659 145 ---NK-----VDGIAFRRD-EQII-----------ETLPAPMIQDLDVYRVGw-------------------------eL 179 Synechocystis sp. P...
15641715 350 RVPHPKYGDAkip---ayDMIKTSVNIMRGCFGG----CSFCSITEH----------EGRIIQNRSQESIINELKEIRDK 412 Vibrio cholerae
15673150 272 INSLPPDFDGfdfskyftDNLWIPIYTSRACVNK----STFCTIPNAsg------gkFRHMPAKKVVENMEVVKEKYGIS 341 Lactococcus lactis ...
18312415 212 RNSLPWSTFF--------KHPIAAVISYKGCPLN----CLACGGSNYtysavfgrrgLGRKSPETLVEEFREITERLKIP 279 Pyrobaculum aerophilum
15607354 153 RDELPTVLAD--------GFAASVFS-TRGCPYR----CTFCGTGAMs---------AMLGKDSYRAKSVDAVVDEIDYL 210 Mycobacterium tuber...
13542209 209 KGHLPYADWL--------RNPEGFTMIERGCQLN----CGFCGGSNFayksn-famnYQFRDPCRIAEEIEMS-QDILGS 274 Thermoplasma volcanium
16081365 180 KGHLPYADWL--------RNPEGFTLIERGCQLN----CGFCGGSNFsyknn-fainYQFRDPCRVVDEIELS-QEILGS 245 Thermoplasma acidop...
16082367 171 --DWPWEGPY-----------VKKAIDLLGEAGY----RKKDLIF------------YMLYNFWDEIHKKGDTPEDFLLR 221 Thermoplasma acidop...
17229515 260 ASTLSPYIQP--------G---LLIETSRGCWWGqkhhCTFCGLNGSgi-------nYRSKSPDRVLKEFTQLCERYGLR 321 Nostoc sp. PCC 7120
13474043 181 IDHRRYSYWG--------GKRAVVMQFSRGCPHL----CNYCGQ-------------RGFWTR-WRHRDPKKFAQEIAWL 234 Mesorhizobium loti
16331659 180 VDLKKYSYYG--------GKQAVVIQFSRGCPHL----CNYCGQ-------------RGFWAR-WRHRDPKKFAQEIVWL 233 Synechocystis sp. P...
15641715 413 VPGFTGVISDLGGP------TAN----------MYRLGCSDPKAEANCRRPSCVFPGICH------KLNTDHKHt----- 465 Vibrio cholerae
15673150 342 HFSFVDETFLVPKMkqiaklLIDneqkdiswycETRFSKLLTADTTQILRKGGCSNIQFGles-ynQRVLDLMDknidia 420 Lactococcus lactis ...
18312415 280 VF-FVGDLQYLGRR-------YL----------EEFAELLRRKKPSVEL----IFEFFTP------------PP------ 319 Pyrobaculum aerophilum
15607354 211 VSDYDVNFLSITDDl----fISK----------HPGSQQRAADFANAVLRRGISVNFMVD------IRLDSVV------- 263 Mycobacterium tuber...
13542209 275 PVFIAGDIALAGPH-------YY----------ERLFKCLNERRIDIPLLTEYFKPFNEDyvkslsKTVEDFS------- 330 Thermoplasma volcanium
16081365 246 PVFVVGDLALAGPK-------YY----------EKFFQCLRDRKIDIPILTEYFKPFDEDyareisRSVVDFS------- 301 Thermoplasma acidop...
16082367 222 LK----NLMRWGAS-------------------AYPMRFIPLDALTRTG-------YVSP-------LWTPEKL------ 258 Thermoplasma acidop...
17229515 322 KFQVVDNILDMNHMntvipvLAAgdeay-nifyETKANLRWEHLQQLAQAGVRCIQPGIEsm---hNSILKLMNkgntaw 397 Nostoc sp. PCC 7120
13474043 235 HREHGVELINLADEn----pTVS----------KKAWR----AFLDALIAENVPVLIVGS------TRADDIVR------ 284 Mesorhizobium loti
16331659 234 HRTHGVQLFNLADEn----pTVN----------KAIWQ----EFCEAIIAENISITIIGS------TRADDIVR------ 283 Synechocystis sp. P...
15641715 466 -IDLYRAARDVDGi-kKVVIASGVRYDLAIESPE----YVRELVTHHVG-------------GYLKIAPEHTEKGPLSMM 526 Vibrio cholerae
15673150 421 wIEPNIINCFEAGisvHLFFMTGFPTETLEEAKNtyhfANEMILKSKKDyglpys-tkgfgtFGLKVGAGVYEKPEVFNI 499 Lactococcus lactis ...
18312415 320 --REVLSLYRRAGd--MVYLQISPESHDEDIRKH----YGRPYDNSSLLe------------FIKNAAELRFERVDLYFM 379 Pyrobaculum aerophilum
15607354 264 -DLDLFKHLHRAG---LRRVFIGVETGSYEQLRA----YRKQILTRGQDaa-----------dTINALQQLGID-VIPGT 323 Mycobacterium tuber...
13542209 331 -MEISPETYDENV---RSWNKSGYSNKDMERSFS----LAEKYGSKKFD-------------VYFSIGLSHQNKKNVMDT 389 Thermoplasma volcanium
16081365 302 -MEISPETSDENV---RNWNKSGYSNDDLERSLK----LAERYGSKKFD-------------VYFSIGLSHQDYKNVLDT 360 Thermoplasma acidop...
16082367 259 --EMIADVRRVLG---FAGTWVPYRALADKFIYY----PQIAHLPRYILk-------------SSFLSSAWYGLPSAVDI 316 Thermoplasma acidop...
17229515 398 mNVQLLKWARELGiivFWNILADFPGESDEWYVEmmewLPLIAHLQPPSgaseirydrfspyYERPSDWGLNLSPLRPYK 477 Nostoc sp. PCC 7120
13474043 285 -DADILHLYRKAG---VIRWLLGMENTDEQTLQL----IRKGGSTS--Sdr-----------eAIRLLRKHGILSMATWV 343 Mesorhizobium loti
16331659 284 -DADILHLYRRAG---VERFLLGMENTNEATLKH----IRKGSKTS--Tdr-----------eAIRLLRQHNILSLATWV 342 Synechocystis sp. P...
15641715 527 MKPGMGTYDRFKEL-------------FEKYSAEAGKK--------QYLIPYFIAAHPGTEDEDMVNLALWLKSNNYRC- 584 Vibrio cholerae
15673150 500 EILEPADDEDLRLSrdynihegltsdeAKQLVSTMRSSkis--lqtSFDAQQFDIEFPKSILPSEIDLINEREKRAAERs 577 Lactococcus lactis ...
18312415 380 VGLPMQTPENVKGLgd----------fFLELAKRGGGAln-----aFVAPLAPFVDPGSPAFHNPSKYGYVILARSFEEh 444 Pyrobaculum aerophilum
15607354 324 IMFHPTVQPDELR----------------ETVRLLRAT----------KYTVGFKFMS--RIVPYPG-TPLYQAYSDAG- 373 Mycobacterium tuber...
13542209 390 VEYAGNIMKGYMRSsm----------rMSTFISPIAPFvdp---gsLWYEKPDLYGFKIYGRSVSDVYRILDLGRTWYDf 456 Thermoplasma volcanium
16081365 361 VEYAGKLMRDFNGSqm----------kLSTFISPIAPFvdp---gsLWYEKSEMYGFKVFARTIADIYHILDTGKTWYDf 427 Thermoplasma acidop...
16082367 317 EWTGPLTSEGYRMS--------------KGANSSICPD---------IVEPSMLSMYFVVSNGEMPQSNNEGGLAKKTG- 372 Thermoplasma acidop...
17229515 478 YVYPLAPEILSELAyffedqnnlvtryATEENEQTSEKterpglenLKLWVNQWNRLWQSLYYKEHKPEYLPILSMNDSg 557 Nostoc sp. PCC 7120
13474043 344 AGFEDEGFRDLWRGfrql------iayDPDQIQALYVTp--------HRWTPFFRIARDRKVIQKDARLWDYKHQVLQM- 408 Mesorhizobium loti
16331659 343 TDFEEVRDRDFIQAlkql------lyyDPDQIMSLYVTp--------HRWTSFYGIASERRVIQLDQTKWDYKHQVLAA- 407 Synechocystis sp. P...
15641715 585 ----------DQVQNFYPSPMCNATAMYHAEVNPlkRVKYKKp---EKVPVAKGE-----------------AQRRLHKA 634 Vibrio cholerae
15673150 578 ykvygfcfenESLKINRYVSLIIDEETQMTLLYNvkHGIFLSyp-tSDLQIGNAKitfaldniksdlayydfLELENSQE 656 Lactococcus lactis ...
18312415 445 rrll-laerwYMMLNYETTTMTRSQIAEATYNAVesLARAKYi---AGIIDDEYLgavletvknarsgappvGLNSKETV 520 Pyrobaculum aerophilum
15607354 374 ----------YLTAKWPLGQWEFVDP----EASR--VYADVV----AKVAPDvg-----------------iSFDEAEAY 416 Mycobacterium tuber...
13542209 457 ---------lDYETNWMTKDDIVNSTYDAEIRMT--QLRYEV----GEITEEARDt----------------IIRNVMNY 505 Thermoplasma volcanium
16081365 428 ---------lDYETQWMSREDIVNATYDAEIRMT--QIRYDV----GDIDRETMEn----------------IIRNVQNY 476 Thermoplasma acidop...
16082367 373 ----------SRSTKHVILPSFLSEASHPSFFSR--LKSVSR----SGAPFPWPN------------------IAQASAG 418 Thermoplasma acidop...
17229515 558 slitiydsrpCATESLLFLEGLAYWVYKVCDRALtyREVVSEinkkLDVPVSWDEifpivselrerkilldiDGRLLSLA 637 Nostoc sp. PCC 7120
13474043 409 ----------TRLKPWMLFFSVKLIEL--AVQSR--PKALAR----ILFHPDPEQrhsmrwy---tkmgrrvWFREVWGF 467 Mesorhizobium loti
16331659 408 ----------THMPPWRIFLWVKLIEI--LLQTR--PKALWR----LLFQPNKASrrgmywf---tlmgrrvLVHELINF 466 Synechocystis sp. P...
15641715 635 LLRYHDPAnwp---mirEALIAMGKRHLIGDRP 664 Vibrio cholerae
15673150 657 KYSTMDEIfegkyklclNDYFFEHYNSTDLLIY 689 Lactococcus lactis subsp. lactis
18312415 521 REEELYPKkfwisyltpRSVAEIIRYSLGRLA- 552 Pyrobaculum aerophilum
15607354 417 FLS--RLD----------EWENVIAGRIAEATS 437 Mycobacterium tuberculosis H37Rv
13542209 506 REGNNYCRn-------dRMDKHLAYMSKDIEWS 531 Thermoplasma volcanium
16081365 477 RRGNNYCRs-------nRVDKHLAYMSKDIEWS 502 Thermoplasma acidophilum
16082367 419 VSLSNLT-------------------------- 425 Thermoplasma acidophilum
17229515 638 LKGSCSPYlsvselpagYIDLHEFRRHNSKSSE 670 Nostoc sp. PCC 7120
13474043 468 LARDGRVK----------DGPTLAEFWGTPQDA 490 Mesorhizobium loti
16331659 467 FFGDRRVK----------NGPTLQEFWGMPQEH 489 Synechocystis sp. PCC 6803
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