2QGQ


Conserved Protein Domain Family
Elp3

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smart00729: Elp3 
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Elongator protein 3, MiaB family, Radical SAM
This superfamily contains MoaA, NifB, PqqE, coproporphyrinogen III oxidase, biotin synthase and MiaB families, and includes a representative in the eukaryotic elongator subunit, Elp-3. Some members of the family are methyltransferases.
Statistics
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PSSM-Id: 214792
Aligned: 275 rows
Threshold Bit Score: 68.5824
Threshold Setting Gi: 74558392
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2QGQ_A      4 PYAYVKISDGCDRG--CTFCSIPSFkG------S-LRSRSIEDITREVEDL-----LKEGKKEIiLVAQDTTSYGIDLYR 69  Thermotoga maritim...
Q97Z27     25 WKSISVTGTYCAFN--CKHCG------------RrVLESMIDGSTQGKIEKeimeaISRGDEGI-------ILSGGSTSR 83  Sulfolobus solfata...
O67770     45 INTLLTYPSGCHAT--CAYCGLQKAreieyskknfIRVEWPTVKTDEIIER---------TKQVgHAERLCISQITHPRA 113 Aquifex aeolicus
Q9VPF7    127 TATIMLMGDTCTRG--CRFCSVKTAr--------kPPPLDVNEPVNTATAI-----ASWGLDYI--VLTSVDRDDLPDGG 189 fruit fly
Q9K7C9     57 TATFMILGDVCTRA--CRFCAVKTGl---------PNELDLQEPERVAESVeimglKHAVITAV---ARDDLKDGGAGV- 121 Bacillus halodurans
NP_377870  25 WRMVSVTGTACAFN--CDHCN------------RrILEGMEDASTREK--M-----KNVLEKVIkEGHRGLILSGGSSV- 82  Sulfolobus tokodai...
NP_148555  48 TATFMIMGDTCTRG--CRFCY-----V------KkGVPEPLDPLEPYKVAL-------AVDALGlDYVTLTSVDRDDLPD 107 Aeropyrum pernix K1
NP_595577 121 TATIMLMGDTCTRG--CRFCSVKTSrR------PgPLDPNEPENTAEAIKQ-------WNLGYI---VLTSVDRDDLTDL 182 Schizosaccharomyce...
NP_440319  50 TATFLIMGPACTRA--CPYCDi----D------FeKKPQPLDSTEPERLAI-------AVKRLN--LKHVVITAVNRDDL 108 Synechocystis sp. ...
NP_247579  35 ERALFLGWY-CNLKqpCKFCYMATQknkik-dprkARRRLESVLAEAILMK----------RIGw--KLEFISGGYGYTp 100 Methanocaldococcus...
2QGQ_A     70 K-Q---ALPDLLRRLNSLNGE----FWIRVXYLH--PDHLTEEIISAXLELDkvVK-YFDVPVQHGSDKILKLXGRTKSS 138 Thermotoga maritim...
Q97Z27     84 GdV---PIWRYSNLLKRYSDr----LTIIAHTGV----VKNEEIARKFKESG--VK-IALLDMVSDNDAIKDILGQPFTV 149 Sulfolobus solfata...
O67770    114 IrDt----KYILEKVHRELGd----KIFISILLN--ATGHTYEDLEDYKRLG--AE-TLTVALDAATPELFEKLRGRPMN 180 Aquifex aeolicus
Q9VPF7    190 SeH-------IAETVREIKAr----NSNIFVECLvpDFRGNLECVKTIANSG--LD-VYAHNIETVEKLTPYVRDRRAHY 255 fruit fly
Q9K7C9    122 -------FAETVRAVRRRNPF-------CTIEVLpsDMMGNDDNLKTLMDAR--PN-ILNHNIETVRRLTPR-VRARATY 183 Bacillus halodurans
NP_377870  83 ---------RGEVPIWRYSDLlsnyANKLTFIAHt-GVVRNPEIAEKFAKAG--VK-IALLDMVGDNETIRDVLKQPFTV 149 Sulfolobus tokodai...
NP_148555 108 GgAs--HFAATVRAIKRLRPd---tIVEALIp----DFQGVEEHVRLVAASG--LE-VLAHNIETVERLTPLVRDRRAGY 175 Aeropyrum pernix K1
NP_595577 183 GaN---HIAKTIQKIKEKAPH-------ILVEALtpDFSGRMDLVEIVAKSG--LD-VFAHNVETVEELTPFVRDRRATY 249 Schizosaccharomyce...
NP_440319 109 PdGgasQFVSCIEAIRKISP-------GTTIEVLi-PDLCGNWQALAALLEA--APeVLNHNMETV-PRLYKRVRPQADY 177 Synechocystis sp. ...
NP_247579 101 --K---EINDIAEMVAYVQKCr---QYLNVGVID--LDNINLDVIEGVVGAV--ETv----------SKDRDWICPGKPL 158 Methanocaldococcus...
2QGQ_A    139 --------EELKKXLSSIRERFp-DAVlRTSIIVGFPGETEEDFEELKQFVEEIQFDKLGAFVYS--DEEGTVAFNLKEK 207 Thermotoga maritim...
Q97Z27    150 --------DDYLNSFKYLKKVN--IKI-VPHVILGLSKKGLEGDLESIRLLQEVNPDALIIVGLM--PLVGTQMNASR-- 214 Sulfolobus solfata...
O67770    181 sphrwetyWKVLEWCADIMGDG---HV-GAHLIVGLG-ETEEEMVRTIQRVRDLGGR-THLFSFW--PEEGSLMEKEK-- 250 Aquifex aeolicus
Q9VPF7    256 --------RQTLQVLTEAKRFNpnLIT-KSSIMLGLG-ETDEEIENTLKDLREAGVDCVTLGQYM-------QPTNKHLK 318 fruit fly
Q9K7C9    184 --------ERSLEFLRRAKEMQpdIPT-KSSLMIGLG-ETKDEIIETMDDLRANNVDIMTIGQYLq-PTKKHLKVQKY-- 250 Bacillus halodurans
NP_377870 150 --------DDYLNSFKYLKSAG--IKI-APHVIVGLSRKGIDGDLHAIELLKEVNPDTVIIVGLM--PLVGTRNTRQP-- 214 Sulfolobus tokodai...
NP_148555 176 --------RQSLRVLEIAKEEG--VVT-KSSILLGLG-EDKSEVIEAMRDLRSVGVDILVLSQYYrpSRKQLPVAKRY-- 241 Aeropyrum pernix K1
NP_595577 250 --------RQSLSVLKHVKKTCphLIT-KTSIMLGLG-ETDAEILTTLKDLLEHNVDVVTFGQYM----RPTKRHLKVQE 315 Schizosaccharomyce...
NP_440319 178 --------DQSLELFNQAKRILpkVYT-KSGIMVGLG-ETDAEVRQVMEDLRRVDCDILTIGQYL--QPSQKHLGVKE-- 243 Synechocystis sp. ...
NP_247579 159 --------DKIKDNLLKAKELG--LKT-GITIILGLG-EKEEDIEKLLNLIEELDLNRITFYSLN--PQKGTIYENKPSV 224 Methanocaldococcus...
2QGQ_A    208 VDPEXAKRRQEEL 220 Thermotoga maritima MSB8
Q97Z27    215 --PPTPEEIIVAL 225 Sulfolobus solfataricus
O67770    251 PCPAPQYRRVQMA 263 Aquifex aeolicus
Q9VPF7    319 VIEYVTPEKFKHW 331 fruit fly
Q9K7C9    251 YHPDEFAELKEIA 263 Bacillus halodurans
NP_377870 215 ---TPQELIAALR 224 Sulfolobus tokodaii str. 7
NP_148555 242 ----SLSEFRELA 250 Aeropyrum pernix K1
NP_595577 316 YVHPKKFEYWKEV 328 Schizosaccharomyces pombe 972h-
NP_440319 244 FVTPEQFDVWRIY 256 Synechocystis sp. PCC 6803
NP_247579 225 ----TTIEYMNWV 233 Methanocaldococcus jannaschii DSM 2661
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