5FQD: Structural basis of Lenalidomide induced CK1a degradation by the crl4crbn ubiquitin ligase

PDB ID: 5FQDDownload
MMDB ID: 136789
PDB Deposition Date: 2015/12/9
Updated in MMDB: 2019/04
Experimental Method:
x-ray diffraction
Resolution: 2.45  Å
Source Organism:
Similar Structures:
Biological Unit for 5FQD: trimeric; determined by author and by software (PISA)
Molecular Components in 5FQD
Label Count Molecule
Proteins (3 molecules)
1
DNA Damage-binding Protein 1
(Gene symbol: DDB1)
Molecule annotation
1
Protein Cereblon
(Gene symbol: CRBN)
Molecule annotation
1
Casein Kinase I Isoform Alpha
(Gene symbol: CSNK1A1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
ZINC IONZINC ION
2
1
S-LenalidomideS-Lenalidomide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303