U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Tprg1l transformation related protein 63 regulated 1 like [ Mus musculus (house mouse) ]

    Gene ID: 67808, updated on 14-May-2024

    Summary

    Official Symbol
    Tprg1lprovided by MGI
    Official Full Name
    transformation related protein 63 regulated 1 likeprovided by MGI
    Primary source
    MGI:MGI:1915058
    See related
    Ensembl:ENSMUSG00000029030 AllianceGenome:MGI:1915058
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tprgl; mover; Svap30; 1200015A19Rik
    Summary
    Enables identical protein binding activity. Predicted to be involved in regulation of glutamatergic synaptic transmission. Predicted to be located in calyx of Held. Predicted to be active in synaptic vesicle. Is expressed in several structures, including gut; hemolymphoid system gland; male reproductive gland or organ; nervous system; and nose. Orthologous to human TPRG1L (tumor protein p63 regulated 1 like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 110.0), lung adult (RPKM 103.0) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Location:
    4 E2; 4 83.88 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (154241942..154246763, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (154157485..154162306, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene transformation related protein 73 Neighboring gene STARR-positive B cell enhancer ABC_E4737 Neighboring gene predicted gene, 26036 Neighboring gene STARR-positive B cell enhancer ABC_E1045 Neighboring gene WD repeat containing, antisense to Trp73 Neighboring gene STARR-seq mESC enhancer starr_12229 Neighboring gene multiple EGF-like-domains 6 Neighboring gene 60S ribosomal protein L24 pseudogene Neighboring gene Rho guanine nucleotide exchange factor 16 Neighboring gene predicted gene, 52687

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (2)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calmodulin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in calyx of Held ISO
    Inferred from Sequence Orthology
    more info
     
    located_in calyx of Held ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extrinsic component of synaptic vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in presynapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in presynapse IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in synaptic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in synaptic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synaptic vesicle ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    tumor protein p63-regulated gene 1-like protein
    Names
    mossy-fiber terminal-associated vertebrate-specific presynaptic protein
    synaptic vesicle associated protein of 30 kD
    transformation related protein 63 regulated like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026388.2NP_080664.1  tumor protein p63-regulated gene 1-like protein

      See identical proteins and their annotated locations for NP_080664.1

      Status: VALIDATED

      Source sequence(s)
      AI840915, AK004324, AK004777, BY739996
      Consensus CDS
      CCDS19011.1
      UniProtKB/Swiss-Prot
      B1AX99, Q8BTC6, Q9DBS2
      Related
      ENSMUSP00000030896.9, ENSMUST00000030896.15
      Conserved Domains (1) summary
      pfam12456
      Location:61162
      hSac2; Inositol phosphatase

    RNA

    1. NR_151647.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AI840915, AK004324, AK004777, AL806525, BY739996

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      154241942..154246763 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539129.4XP_006539192.3  tumor protein p63-regulated gene 1-like protein isoform X1

      Conserved Domains (2) summary
      pfam12456
      Location:174264
      hSac2; Inositol phosphatase
      cl02324
      Location:93197
      DUF721; Protein of unknown function (DUF721)