cyc1 cytochrome c-1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cyc1provided by ZNC
Official Full Name: cytochrome c-1provided by ZNC
Primary source: ZFIN:ZDB-GENE-031105-2
See related: Ensembl:ENSDARG00000038075 AllianceGenome:ZFIN:ZDB-GENE-031105-2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb80h03; sr:nyz104; im:6911272; wu:fb80h03; zgc:123089
Summary: Predicted to enable electron transfer activity; heme binding activity; and metal ion binding activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be integral component of membrane. Predicted to be part of mitochondrial respiratory chain complex III. Is expressed in several structures, including adaxial cell; digestive system; eye; midbrain; and musculature system. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 6. Orthologous to human CYC1 (cytochrome c1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (50381572..50390093)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (50382353..50390874)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fj50h05.y1 (e-PCR)
- UniSTS:199482

fb80h03.x1 (e-PCR)
- UniSTS:203458

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables electron transfer activity	IEA Inferred from Electronic Annotation more info
enables heme binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables ubiquinol-cytochrome-c reductase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mitochondrial electron transport, ubiquinol to cytochrome c	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
part_of mitochondrial respiratory chain complex III	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
located_in respirasome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cytochrome c1, heme protein, mitochondrial

NP_001032470.1

EC 7.1.1.8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.