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    calm2a calmodulin 2a (phosphorylase kinase, delta) [ Danio rerio (zebrafish) ]

    Gene ID: 336121, updated on 11-Apr-2024

    Summary

    Official Symbol
    calm2aprovided by ZNC
    Official Full Name
    calmodulin 2a (phosphorylase kinase, delta)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030804-3
    See related
    Ensembl:ENSDARG00000031427 AllianceGenome:ZFIN:ZDB-GENE-030804-3
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb815; calm2d; CaMalpha; zgc:73045; wu:fj49d04
    Summary
    Predicted to enable calcium ion binding activity and enzyme regulator activity. Predicted to be involved in calcium-mediated signaling. Is expressed in several structures, including axis; mesoderm; nervous system; neural tube; and pancreas primordium. Human ortholog(s) of this gene implicated in long QT syndrome 15. Orthologous to human CALM2 (calmodulin 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    Location:
    chromosome: 13
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (8777633..8785297, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (8445610..8453274, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat domain 7A Neighboring gene si:ch211-93n23.7 Neighboring gene si:ch73-105b23.6 Neighboring gene epithelial cell adhesion molecule

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of ryanodine-sensitive calcium-release channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    calmodulin 2a (phosphorylase kinase, delta)
    Names
    CALMx3
    calmodulin 2, alpha
    calmodulin 2, delta
    NP_956290.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199996.2NP_956290.1  calmodulin 2a (phosphorylase kinase, delta)

      See identical proteins and their annotated locations for NP_956290.1

      Status: PROVISIONAL

      Source sequence(s)
      BC068339
      UniProtKB/Swiss-Prot
      Q4V949, Q6PI52
      UniProtKB/TrEMBL
      B2GQW3
      Related
      ENSDARP00000010393.8, ENSDART00000021083.10
      Conserved Domains (1) summary
      PTZ00184
      Location:1149
      PTZ00184; calmodulin; Provisional

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      8777633..8785297 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395306.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      190895..198241 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)